Multiple extra-adrenal and thoracic pheochromocytomas

Braedel, H. U.; Lindinger, Angelika; Berberich, R.; Schindler, E.; Crisp-Lindgren, N.

doi:10.1016/0090-4295(86)90094-4

Cited by 8 publications

(2 citation statements)

References 7 publications

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“…CT of the abdomen should be done first, followed by chest and neck imaging if the abdominal CT is negative. Spiral CT is preferred for small thoracic tumors and CT can be used for suspected supradiaphragmatic PHEO 12‐20…”

Section: Anatomical Imagingmentioning

confidence: 99%

Anatomical and Functional Imaging of Metastatic Pheochromocytoma

Ilias

Pacák

2004

Annals of the New York Academy of Sciences

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Although in the majority of patients with pheochromocytoma the tumor is localized in the adrenal, up to 26% of patients have malignant/metastatic disease. Metastatic disease should be ruled out before initial surgery is attempted. Anatomical imaging modalities (computed tomography or magnetic resonance imaging) should be done first over the adrenals, and if negative over the abdomen and if no tumor is found, then the chest and neck should be covered. Regardless of the anatomical imaging results functional imaging with [123-I]- or [131-I]-metaiodobenzylguanidine (MIBG) scintigraphy should be done to corroborate the diagnosis. Negative MIBG scans should be followed by positron emission tomography (PET) studies with specific ligands like [18-F]-dopamine. Persistently negative evaluations should be followed by PET studies with non-specific ligands such as [18-F]-deoxyglucose or somatostatin receptor scintigraphy.

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Section: Anatomical Imagingmentioning

confidence: 99%

Anatomical and Functional Imaging of Metastatic Pheochromocytoma

Ilias

Pacák

2004

Annals of the New York Academy of Sciences

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“…Uptake of l31I-MIBG is a new method of identi fying a tumor originated from chromaffin tissues, be cause MIBG, which resembles noradrenalin in its molec ular structure, is thought to enter the chromaffin tissue by the same mechanism as that of the neurotransmitter or hormone [1], Visualizations of adrenal or extra adrenal pheochromocytomas with l31I-MIBG have been reported [9][10][11]. But l3lI-MIBG scintigraphy of paragan glioma in the bladder has not been described in the liter ature.…”

Section: Discussionmentioning

confidence: 99%