Multiple fibro-osseous lesions of the jaws: A report of a rare case with a literature review

Makkad, Ramanpal Singh; Naidu, Giridhar S; Nagi, Ravleen; Sagtani, Alok; Patil, Santosh; Shrivastava, Swatantra

doi:10.5624/isd.20210021

Cited by 5 publications

(6 citation statements)

References 14 publications

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“…The treatment of JTOF and JPOF is complete resection, although recurrence is higher than in COF. Seventy percent of OF involve the mandible, with 22% found in the molar region of the maxilla, the ethmoids, orbital regions, and rarely the petrous bone [1]. OF commonly occurs as a solitary lesion, although rarely seen in multiple sites or shows multiple, familial, or sequential presentations [1].…”

Section: Discussionmentioning

confidence: 99%

“…Fibro-osseous lesions (FOL) of the jaw bones include fibrous dysplasia, ossifying fibroma (OF), florid osseous dysplasia, cemento-ossifying fibroma (COF), and focal osseous dysplasia [1].…”

Section: Introductionmentioning

confidence: 99%

“…The cell of origin is unknown, although it is presumed to arise from multipotential mesenchymal cells in the periodontal ligament space [3]. OF occurs as solitary lesions and rarely as multiple lesions [1]. However, Makkadi et al [1] reported a rare case with multiple FOL of the jaws in four quadrants and quoted other authors who have reported cases of OF in multiple sites: Takeda and Fujioka [4] in three quadrants; Hauser et al [5], one case of bilateral lesions in the maxillary sinuses; Hwang et al [6], one case in all four quadrants; Bertolini et al [7], one in the maxilla and mandible; Canger et al [8], two cases of multiple familial OFs involving two quadrants in the mandible and maxilla.…”

Section: Introductionmentioning

confidence: 99%

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Ossifying Fibroma in the Maxilla and Mandible: A Case Report With a Brief Literature Review

Chidzonga¹,

Sunhwa²,

Makunike-Mutasa³

2023

Cureus

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Fibro-osseous lesions in the jaw bones include fibrous dysplasia, ossifying fibroma (OF), cemento-ossifying fibroma, florid osseous dysplasia, and focal osseous dysplasia. OF is the most common fibro-osseous tumor that presents as a slow-growing well-encapsulated benign neoplasm composed of varying amounts of bone or cement-like tissue in a fibrous stroma well-demarcated from the adjacent normal bone. OF is most common in the jaw bones, with a predilection for the mandible. OF usually occur as solitary lesions and rarely as multiple lesions in a patient. We present clinical and radiologic features, histopathology, and surgical management of a rare case with large synchronous OFs in the mandible and maxilla and a brief review of the literature.

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Section: Discussionmentioning

confidence: 99%

“…Fibro-osseous lesions (FOL) of the jaw bones include fibrous dysplasia, ossifying fibroma (OF), florid osseous dysplasia, cemento-ossifying fibroma (COF), and focal osseous dysplasia [1].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Ossifying Fibroma in the Maxilla and Mandible: A Case Report With a Brief Literature Review

Chidzonga¹,

Sunhwa²,

Makunike-Mutasa³

2023

Cureus

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“…They encompass two major lesions: fibrous dysplasia and ossifying fibroma. Cemento-ossifying fibroma (COF) is a definite form of benign fibro-osseous tumor affecting the craniofacial region (70%), principally in the jaws [ 1 , 2 ]. Most individuals are diagnosed in their second or third decades of life [ 3 , 4 ], and it is more common in women than in men in the ratio of 4:1 [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

A Rare Case of Cemento-Ossifying Fibroma: A Case Report

Aravindan¹,

Kumar²,

P³

et al. 2023

Cureus

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Benign fibro-osseous lesions are a group of pathological conditions characterized by the replacement of normal bone with cellular fibrous connective tissue that undergoes mineralization. The most common types of benign fibro-osseous lesions include fibrous dysplasia, ossifying fibroma, and osseous dysplasia. However, diagnosing these lesions can be challenging due to their overlapping clinical, radiological, and histological features, which can cause a diagnostic dilemma for surgeons, radiologists, and pathologists. One rare type of benign fibro-osseous lesion is the cemento-ossifying fibroma (COF), which is a definitive form of a benign fibro-osseous tumor that affects the craniofacial region, particularly the jaws (70%). Here, we present a case of COF in a 61-year-old female patient in the maxillary anterior region. Due to a clear distinction between the lesion and healthy bone, the lesion was treated with conservative surgical excision followed by curettage and primary closure. However, differential diagnosis of COF can be highly challenging for clinicians due to its overlapping features with other fibro-osseous lesions like Paget’s disease and fibrous dysplasia. Ossifying fibroma and fibrous dysplasia often present a histopathological, clinical, and radiological overlap. The post-operative follow-up after eight months was unpredictable, with a radiological picture showing the increased thickness of the frontal bone, parietal bone, and maxilla with obliteration of marrow spaces, alteration of the trabecular pattern with a cotton wool/ground glass appearance, and reduced maxillary sinus space. Proper evaluation and diagnosis of fibro-osseous lesions are necessary before arriving at a final conclusion. Cemento-ossifying fibroma in the maxillofacial skeleton is uncommon, and after eight months, the recurrence rate is rare. This case highlights the importance of considering COF as a differential diagnosis for fibro-osseous lesions in the maxillofacial region and the necessity for proper evaluation and diagnosis to determine the appropriate treatment plan and prognosis. In summary, the diagnosis of benign fibro-osseous lesions can be challenging due to their overlapping features, but early diagnosis and proper evaluation are essential for successful treatment outcomes. COF is a rare type of benign fibro-osseous lesion where other fibro-osseous lesions in the maxillofacial region should be considered as a differential diagnosis, and the necessary steps should be taken to confirm the diagnosis before arriving at a final conclusion.

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“…Fibro-osseous lesions of the maxilla and mandible includes fibrous dysplasia, ossifying fibroma (OF), florid osseous dysplasia, cemento-ossifying fibroma (COF), and focal osseous dysplasia. [ 1 2 ] Peripheral OF are seen as a benign tumor, and may be sessile or pedunculated growth, most commonly affecting the maxilla as compared to the mandible. It arises from the interdental papillae of the maxillary gingiva.…”

Section: Introductionmentioning

confidence: 99%

Peripheral Ossifying Fibroma of Maxillary Gingiva with Calcification: A Case Report

Tidke,

Agarwal,

Kini

et al. 2023

Journal of Pharmacy and Bioallied Sciences

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Peripheral ossifying fibroma is presented as an exophytic growth with a smooth surface. It is located mostly on the gingiva, and it is an unusual growth of gingiva that occurs after irritational trauma. It is seen in the later decade of life, with the calcifications in the lesion in advanced stages seen on radiographic images. In the present case, a 50-year-old male reported with a huge gingival growth in the left maxillary posterior gingival region; when radiograph was taken, it showed calcifications. The patient was treated by surgical excision of the growth.

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Multiple fibro-osseous lesions of the jaws: A report of a rare case with a literature review

Cited by 5 publications

References 14 publications

Ossifying Fibroma in the Maxilla and Mandible: A Case Report With a Brief Literature Review

Ossifying Fibroma in the Maxilla and Mandible: A Case Report With a Brief Literature Review

A Rare Case of Cemento-Ossifying Fibroma: A Case Report

Peripheral Ossifying Fibroma of Maxillary Gingiva with Calcification: A Case Report

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