Multiple Fresh Coronary Occlusions in Patients With Antecedent Shock

Histopathological Changes in the Coronary Arteries following Shock or Hypotension in Man

“…C linically 1 to 8 p er cent o f the p atien ts with antecedent shock or h y p o tensive state present co ro n ary throm bosis o r acute co ro n ary insufficiency (1,5,19). O ur results support the view th at the changes in the c o ro n ary arte ry w alls m ay he an im p o rtan t facto r in leading to this throm bosis.…”

Significance of coronary arterial thrombus in transmural acute myocardial infarction. A study of 54 necropsy patients.

“…Others believe that coronary thrombi follow the AMI, resulting from the slowed flow (in the coronary artery) produced by the infarct itself. [5][6][7][8][9][10][11][12][13][14][15][17][18][19][20] This view is based primarily on the absence of coronary thrombi in a significant percentage of patients with fatal transmural AMI,4-10, 13, 14, 18 their absence in patients with fatal coronary events other than transmural AMI (sudden coronary death,15' 34 3 subendocardial infarcts'4 and angina pectoris36), their increased frequency in patients with relatively longer durations of survival after AMI,5' 10 and their high frequency in patients with severe congestive heart failure or cardiogenic shock with AMI.1" 12,37,38 However, surprisingly little detailed information is available on the status of a coronary artery containing a thrombus in patients with fatal AMI.…”

Clinical Studies on Veratrum Alkaloids. Iii. The Effect of Protoveratrine on Renal Function in Man 1

“…It is well known, for example, that in patients with coronary artery disease abrupt or prolonged falls in blood pressure may lead to coronary occlusion or myocardial infarction (24). However, the lowered blood pressure which results from the use of protoveratrine, at least within a certain dosage range, appears to be due primarily to a release of arteriolar vasoconstriction and diminution of total peripheral resistance.…”