Multiple Influence of Vibration on Biochemical Brain Indicators

Abstract

Dysfunction of the nervous system is one of the main manifestations caused by vibration. With repeated exposure to vibration, significant changes in the activity of enzymes and the content of the studied substrates in the brain tissue of experimental animals are observed. The observed changes in the activity of enzymes and the content of the studied substrates of brain tissue and the associated disturbances in the basic biochemical metabolic processes may be the direct cause of serious disorders of the functions of the nervous system. According to research results, it was revealed that exposure to general vibration leads to disturbances in the process of transamination of alanine-, aspartic-amino acids, cholinesterase, the activity of enzymes of the tricarboxylic acid cycle (GDH, SDH and MDH), alkaline phosphatase, ribonuclease and lactate dehydrogenase, as well as the content of total protein, serotonin, histamine and acetylcholine in the brain of experimental animals.