Multiple Informant Agreement on the Anxiety Disorders Interview Schedule in Youth with Autism Spectrum Disorders

Storch, Eric A.; May, Jill Ehrenreich; Wood, Jeffrey J.; Jones, Anna M.; Nadai, Alessandro S. De; Lewin, Adam B.; Arnold, Elysse B.; Murphy, Tanya K.

doi:10.1089/cap.2011.0114

Cited by 92 publications

(64 citation statements)

References 33 publications

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“…A previous meta-analysis of CBT trials for anxiety in typically developing youth found that youth often reported lower treatment effect sizes than their parents' reports [54]. These results are concordant with previous studies that have reported poor parent/clinician and child diagnostic agreement on anxiety measures in typically developing youth (e.g., ADIS; [55]) and youth with ASD (e.g., ADIS; [31]). It may be that children with ASD have difficulty reporting on their symptoms due to limited insight into symptoms and/or treatment effects, difficulty reporting on internal states, and secondary to the effects of comorbidity (e.g., inattentive youth may have difficulty participating in evaluations).…”

Section: Discussionsupporting

confidence: 85%

“…In particular, the child's report, when compared to the reports of the parent and clinician, is frequently discrepant [18,27,31]. This disparity may be the result of the child's limited insight into his/her anxiety symptoms (e.g., lack of recognition that anxiety symptoms are clinically significant and/or are impairing) or comorbid conditions (e.g., attention difficulties, oppositional behaviors) [2,5,6,15].…”

Section: Anxiety Informantmentioning

confidence: 99%

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A Systematic Review and Meta-Analysis of Cognitive-Behavioral Therapy for Anxiety in Youth with High-Functioning Autism Spectrum Disorders

Ung

Selles

Small

et al. 2014

Child Psychiatry Hum Dev

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126

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Cognitive-behavioral therapy (CBT) has been developed and modified to treat anxiety symptoms in youth with high-functioning autism spectrum disorders (ASD) but has yielded varying findings. The present report is a systematic review and meta-analysis examining the efficacy of CBT for anxiety among youth with ASD. A systematic search identified 14 studies involving 511 youth with high-functioning ASD. A random effects meta-analysis yielded a statistically significant pooled treatment effect size (g) estimate for CBT (g = -0.71, p < .001) with significant heterogeneity [Q (13) = 102.27, p < .001]. Removal of a study outlier yielded a statistically significant pooled treatment effect size, (g = -0.47, p < .001). Anxiety informant and treatment modality were not statistically significant moderators of treatment response. Findings suggest that CBT demonstrates robust efficacy in reducing anxiety symptoms in youth with high-functioning ASD.

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Section: Discussionsupporting

confidence: 85%

Section: Anxiety Informantmentioning

confidence: 99%

A Systematic Review and Meta-Analysis of Cognitive-Behavioral Therapy for Anxiety in Youth with High-Functioning Autism Spectrum Disorders

Ung

Selles

Small

et al. 2014

Child Psychiatry Hum Dev

Self Cite

196

126

View full text Add to dashboard Cite

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“…Second, internal consistency for the PARS and SRPs were relatively low, which could impact the conclusions. Although psychometrically sound, the PARS has demonstrated fair internal consistency in typically developing youth and in those with ASD [38,40], which has been suggested to relate to the associated but not redundant item content. Third, use of an open trial prevented the incorporation of a control group with which to compare outcome data.…”

Section: Discussionmentioning

confidence: 99%

“…For the current study, severity of physical symptoms of anxiety was assessed using an item from the PARS as rated by the parent, youth, and clinician. The PARS has acceptable reliability and validity [39] and has been shown to be acceptable for use among youth with ASD [40]. Internal consistency ratings for the PARS in the sample were .53 at baseline, and .80 at post-treatment.…”

Section: Pediatric Anxiety Rating Scale (Pars)mentioning

confidence: 90%

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Frequency and Clinical Correlates of Sleep-Related Problems Among Anxious Youth with Autism Spectrum Disorders

Nadeau

Arnold

Keene

et al. 2014

Child Psychiatry Hum Dev

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Sleep-related problems (SRPs) are common and problematic among anxious youth but have not been investigated in anxious youth with autism spectrum disorder (ASD). Participants were 102 youth (ages 7-16 years) with ASD and comorbid anxiety. Youth and their primary caregiver were administered the Pediatric Anxiety Rating Scale. Parents completed the Multidimensional Anxiety Scale for Children-Parent (MASC-P) Report, Social Responsiveness Scale, and the Child Behavior Checklist (CBCL). A measure of SRPs was created from items from the CBCL and MASC-P. Results suggest SRPs were relatively common among youth with ASD and comorbid anxiety. The number of SRPs endorsed directly associated with parent ratings of social deficits, internalizing and externalizing symptoms, and anxiety symptoms, as well as with clinician-rated anxiety symptoms. Parent-rated internalizing symptoms predicted frequency of SRPs over and above social deficits, externalizing symptoms, and parent- and clinician-rated anxiety symptoms. A subset of 40 participants who completed family-based cognitive-behavioral therapy (CBT) experienced reduced SRPs following treatment. Implications, study limitations, and recommendations for future research are discussed.

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Obsessive‐Compulsive Disorder in Adults with High‐Functioning Autism Spectrum Disorder: What Does Self‐Report with the OCI‐R Tell Us?

et al. 2015

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Little is known about the symptom profile of obsessive-compulsive disorder (OCD) in individuals who have autism spectrum disorders (ASD). It is also unknown whether self-report questionnaires are useful in measuring OCD in ASD. We sought to describe the symptom profiles of adults with ASD, OCD, and ASD + OCD using the Obsessive Compulsive Inventory-Revised (OCI-R), and to assess the utility of the OCI-R as a screening measure in a high-functioning adult ASD sample. Individuals with ASD (n = 171), OCD (n = 108), ASD + OCD (n = 54) and control participants (n = 92) completed the OCI-R. Individuals with ASD + OCD reported significantly higher levels of obsessive-compulsive symptoms than those with ASD alone. OCD symptoms were not significantly correlated with core ASD repetitive behaviors as measured on the ADI-R or ADOS-G. The OCI-R showed good psychometric properties and corresponded well with clinician diagnosis of OCD. Receiver operating characteristic analysis suggested cut-offs for OCI-R Total and Checking scores that discriminated well between ASD + versus -OCD, and fairly well between ASD-alone and OCD-alone. OCD manifests separately from ASD and is characterized by a different profile of repetitive thoughts and behaviors. The OCI-R appears to be useful as a screening tool in the ASD adult population.

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Multiple Informant Agreement on the Anxiety Disorders Interview Schedule in Youth with Autism Spectrum Disorders

Abstract: These data suggest that parent and youth agreement regarding the presence of clinical levels of anxiety is markedly poor among youth with ASD. Additionally, clinicians are likely to base their diagnostic impressions on parent report, placing minimal emphasis on child report.

Cited by 92 publications

References 33 publications

A Systematic Review and Meta-Analysis of Cognitive-Behavioral Therapy for Anxiety in Youth with High-Functioning Autism Spectrum Disorders

A Systematic Review and Meta-Analysis of Cognitive-Behavioral Therapy for Anxiety in Youth with High-Functioning Autism Spectrum Disorders

Frequency and Clinical Correlates of Sleep-Related Problems Among Anxious Youth with Autism Spectrum Disorders

Obsessive‐Compulsive Disorder in Adults with High‐Functioning Autism Spectrum Disorder: What Does Self‐Report with the OCI‐R Tell Us?

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