Multiple Masses in a Horse's Tongue Resulting from an Atypical Perineurial Cell Proliferative Disorder

Summary A 12‐year‐old Selle Français mare was presented because of inspiratory stridor, hypersalivation and dysphagia. A mass at the base of the tongue could be visualised by upper airway endoscopy, oral cavity examination and radiographs of the head. The exact localisation, extent of the mass and extent of tissue infiltration could only be defined by magnetic resonance imaging (MRI). This Case Report illustrates the usefulness of MRI to assess the characteristics and extent of such a lesion and describes the appearance of peripheral nerve sheath tumour in the tongue of a horse.

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“…2001). In the tongue of a horse only one case report describes an atypical perineurial cell proliferation (Vashisht et al . 2007).…”

Section: Introductionmentioning

confidence: 99%

“…Human PNSTs are relatively common but occur infrequently in domestic animals (Stoica et al 2001). In the tongue of a horse only one case report describes an atypical perineurial cell proliferation (Vashisht et al 2007).…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging features of a benign peripheral nerve sheath tumour with ‘ancient’ changes in the tongue of a horse

Schneider

Tessier²,

Gorgas

et al. 2010

Equine Veterinary Education

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“…Tumours reported to involve the tongue in horses are rhabdomyosarcoma (Hanson et al 1993;Castleman et al 2011), squamous cell carcinoma (Schuh 1986), benign peripheral nerve sheath tumour (Schneider et al 2010), atypical perineurial cell proliferative lesions (Vashisht et al 2007), multiple myeloma (Markel and Dorr 1986), lymphoma (Rhind and Dixon 1999), mast cell tumour (Seeliger et al 2007) and chondrosarcoma (Wilson and Anthony 2007). This report describes a previously unreported distinctive tumour arising in the tongue of horses.…”

Section: Introductionmentioning

confidence: 99%

Oncology Virtual Issue Articles

2014

Equine Veterinary Education

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Tumours arising from the dorsal surface of the tongue occurred in 3 horses from 14 to 23 years of age. Tumours were surgically excised at a referral hospital (1 case) and on the farm (2 cases) and submitted for histopathology. All tumours were multilobular and composed of vaguely nested, bland, oval to slightly elongated cells with an infiltrative growth pattern. Mitotic activity was not detected. Immunohistochemical studies found that tumour cells were often positive for S-100 and cytokeratin and occasionally positive for vimentin. Tumour cells were negative for glial fibrillary acidic protein, neuron specific enolase, synaptophysin, muscle actin and chromogranin A. Follow-up obtained from 7 months to 2 years following tumour removal indicated no evidence of regrowth or metastasis. The origin of these distinctive tumours is not clear but the immunohistochemical profile suggests the possibility of origin from lingual taste buds. These cases and review of the literature indicate that successful surgical excision of tongue tumours can be performed by practitioners in private practice as well as by surgeons at referral hospitals. © 2012 EVJ Ltd B. A. Valentine et al. 329 Fig 4: Horse tongue tumour, Case 2. Tumour cells are relatively bland oval cells forming poorly defined nests. Haematoxylin and eosin. Bar = 50 mm.

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“…), atypical perineurial cell proliferative lesions (Vashisht et al . ), multiple myeloma (Markel and Dorr ), lymphoma (Rhind and Dixon ), mast cell tumour (Seeliger et al . ) and chondrosarcoma (Wilson and Anthony ).…”

Section: Introductionmentioning

confidence: 99%

Distinctive tumour of the tongue in 3 horses

Valentine

Bildfell

Dunn³

2012

Equine Veterinary Education

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SummaryTumours arising from the dorsal surface of the tongue occurred in 3 horses from 14 to 23 years of age. Tumours were surgically excised at a referral hospital (1 case) and on the farm (2 cases) and submitted for histopathology. All tumours were multilobular and composed of vaguely nested, bland, oval to slightly elongated cells with an infiltrative growth pattern. Mitotic activity was not detected. Immunohistochemical studies found that tumour cells were often positive for S-100 and cytokeratin and occasionally positive for vimentin. Tumour cells were negative for glial fibrillary acidic protein, neuron specific enolase, synaptophysin, muscle actin and chromogranin A. Follow-up obtained from 7 months to 2 years following tumour removal indicated no evidence of regrowth or metastasis. The origin of these distinctive tumours is not clear but the immunohistochemical profile suggests the possibility of origin from lingual taste buds. These cases and review of the literature indicate that successful surgical excision of tongue tumours can be performed by practitioners in private practice as well as by surgeons at referral hospitals.

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Multiple Masses in a Horse's Tongue Resulting from an Atypical Perineurial Cell Proliferative Disorder

Cited by 15 publications

References 11 publications

Magnetic resonance imaging features of a benign peripheral nerve sheath tumour with ‘ancient’ changes in the tongue of a horse

Magnetic resonance imaging features of a benign peripheral nerve sheath tumour with ‘ancient’ changes in the tongue of a horse

Oncology Virtual Issue Articles

Distinctive tumour of the tongue in 3 horses

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