Multiple megacystic tumefactive demyelinating lesions. A case report

J, García Maroto; A, Aranaz Murillo; Suñén, I; Martinez, A. Bergua; Cárdenas, M.E. Gutiérrez

doi:10.1016/j.neurad.2022.04.002

Journal of Neuroradiology

2022

DOI: 10.1016/j.neurad.2022.04.002

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Multiple megacystic tumefactive demyelinating lesions. A case report

García Maroto J

Aranaz Murillo A

I Suñén

et al.

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2023

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Cited by 1 publication

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Pseudocystic inflammatory demyelinating lesions in multiple sclerosis: A clinical, radiological, and pathological description

Cluse,

Fenouil,

Vukusic

et al. 2023

Mult Scler

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Background: Pseudocystic inflammatory demyelinating lesions (PIDLs) are poorly described in MS and might represent a diagnostic challenge. Objectives: We described the clinical, radiological, pathological, and follow-up characteristics of 13 PIDL in 9 MS patients. Methods: We constituted a single-center retrospective case series of PIDLs in MS, defined on MRI as expansive cyst-like lesions, with a fluid-signal content, and a diameter of 1 cm or more. Results: PIDL often occurred at first event (56%), were often asymptomatic (69%), and encircled by a hypo-T2 diffusion-restricted rim and a thin ring-like gadolinium enhancement (100%) on magnetic resonance imaging (MRI). Associated typical MS lesions were constant. Biopsies from two PIDLs displayed classical features of active MS, except for unusual edema. Conclusion: PIDLs are clinically unremarkable and associated with a good outcome. Their easily recognizable MRI features could help avoid biopsy.

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Pseudocystic inflammatory demyelinating lesions in multiple sclerosis: A clinical, radiological, and pathological description

Cluse,

Fenouil,

Vukusic

et al. 2023

Mult Scler

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Multiple megacystic tumefactive demyelinating lesions. A case report

Cited by 1 publication

References 9 publications

Pseudocystic inflammatory demyelinating lesions in multiple sclerosis: A clinical, radiological, and pathological description

Pseudocystic inflammatory demyelinating lesions in multiple sclerosis: A clinical, radiological, and pathological description

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