Multiple Myeloma

Multiple Myeloma

“…On the basis of the present series, and conclusions drawn by other authors (2,12,17,20), the author concludes that definite roentgenologic information is obtainable merely in certain far advanced cases or in classical cases with multiple manifestations. The roentgenographic findings are often uncharacteristic, and a definite diagnosis can only be established by means of supporting biochemical examinations, study of by guest on July 26, 2015 acr.sagepub.com Downloaded from sternal smears and biopsy specimens obtained directly from a focus in the bone.…”

“…This type is regarded as the rarest variety. In a series reported by BAYRD and HECK (2) it occurred in 9 per cent of the cases. In the same eeries, 12 per cent of the cases presented no visible bone abnormalities.…”

“…These tumors occur predominantly in flat bones and in the metaphyses of the long bones, a feature which previously was regarded as characteristic of multiple myeloma. BAYRD and HECK (2) found multiple foci in the bones in 78 per cent of the cases in their series, while JAFFE and LICHTENSTEIN (14) maintain that the classical features are rather an exception than a rule. III.…”

Peripheral Neuritis in Myelomatosis

“…The high incidence of atypical radiological findings has been stressed in recent reviews of this disease (Bayrd and Heck, 1947, and others), and the diagnostic difficulties encountered have been well reviewed by Heiser and Schwartzman (1952).…”

Osteosclerotic Changes in Myelomatosis: Report of a Case

“…Bone lesions are demonstrable in about 80 % of all cases of myelomatosis (BAYRD 1947 andHEISER 1952) and are generally described as purely osteolytic without any signs of reaction of the surrounding cells. Three types of lesions are usually distinguished.…”