Multiple myeloma

Allelic loss at 19q12 and Xq11–12 predict an adverse clinical outcome in patients with mucinous ovarian tumours of low malignant potential

“…Characterised by complex branching papillae, epithelial stratification, nuclear atypia, mitotic activity, and absence of stromal invasion, these tumours are considered to be of LMP. Serous and mucinous tumours comprise the vast majority of cases, with endometrioid, clear cell, and Brenner-type tumours also described (Russel et al, 1994). Low malignant potentials (30 -50%) are mucinous type (Lee and Scully, 2000) and the incidence of mucinous LMPs is high in Japan compared to Western countries (Nakashima et al, 1990;Tamakoshi et al, 1997).…”