In educational policy research, linking specific practices to specific outcomes is an important (though not the only) goal, which can bias researchers (and funders) toward employing purely quantitative methods. Given the context-specific nature of policy implementation in education, however, we argue that understanding how specific practices lead to specific outcomes in specific conditions or contexts is critical to improving education. Qualitative comparative analysis is a method of qualitative research that we argue can help to answer these kinds of questions in studies of educational policies and reforms. Qualitative comparative analysis is a case-oriented research method designed to identify causal relationships between variables and a particular outcome. Distinct from quantitative causal methods, qualitative comparative analysis requires qualitative data to identify conditions (and combinations of conditions) that lead to a particular result; it is context driven, just as many educational reforms must necessarily be. We contend that qualitative comparative analysis has the potential to be of use to educational researchers in investigating complex problems of cause and effect using qualitative data. As such, our aim here is to provide a general overview of the characteristics, processes, and outcomes of qualitative comparative analysis. In so doing, we hope to offer guidance to educational researchers around how and when to use qualitative comparative analysis, as well as recommendations for current educational issues that could be investigated with qualitative comparative analysis.