Multiple Primary Cancers in Patients With Head and Neck Cancer and History of Tobacco Smoking and Drinking

Nakamizo, Munenaga; Kamata, S; Kawabata, Kazuyoshi; Takahashi, Hisaaki; Nigauri, Tomohiko; Hoki, Katsufumi; Uchida, Masaoki; Hiyama, Tomohiko

doi:10.3950/jibiinkoka.96.1501

Nippon Jibiinkoka Gakkai Kaiho

1993

DOI: 10.3950/jibiinkoka.96.1501

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Multiple Primary Cancers in Patients With Head and Neck Cancer and History of Tobacco Smoking and Drinking

Munenaga Nakamizo

S Kamata

Kazuyoshi Kawabata

et al.

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Cited by 3 publications

(2 citation statements)

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“…Recently, multiple primary malignant tumors in the same patient frequently have been found because of the advancing age of patients and improvements in the diagnosis of malignant tumors. In the reports of the 1980s, the incidence of multiple primary malignant tumors in patients with cancer of the head and neck had been about 5%, 1,2 whereas it was Ն10% in the reports after 1990. 3,4 Apparently, this tendency is increasing.…”

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“…In the reports of the 1980s, the incidence of multiple primary malignant tumors in patients with cancer of the head and neck had been about 5%, 1,2 whereas it was Ն10% in the reports after 1990. 3,4 Apparently, this tendency is increasing. Multiple primary malignant tumors are traditionally designated as synchronous tumors or metachronous tumors after a period of 6 months.…”

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See 1 more Smart Citation

Four cases of simultaneous triple primary cancers of the hypopharynx, esophagus, and stomach

Ikeda

Tsukuda

Ishitoya

et al. 2005

Otolaryngol.--head neck surg.

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mentioning

confidence: 99%

mentioning

confidence: 99%

Four cases of simultaneous triple primary cancers of the hypopharynx, esophagus, and stomach

Ikeda

Tsukuda

Ishitoya

et al. 2005

Otolaryngol.--head neck surg.

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Second primary lung cancer after head and neck squamous cell cancer: Population‐based study of risk factors

et al. 2012

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Survival Benefit of Screening for Early Esophageal Carcinoma in Head and Neck Cancer Patients

Horiuchi

Makuuchi

Machimura

et al. 1998

Digestive Endoscopy

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Primary cancer of the head and neck was diagnosed in 676 cases. Systematic endoscopic screening of the upper gastrointestinal tract (including iodine staining of the esophagus) was performed within 1 month of diagnosing head and neck cancer in order to determine the possible presence of a second malignancy. We divided cases in which esophageal cancer was detected into a group in which the initially diagnosed head and neck cancer had been treated curatively and those in which the treatment had been non-curative. A pathological diagnosis of primary esophageal cancer was obtained in 37 cases (5.5%). The incidence of esophageal cancer associated with cancer of the oral cavity or pharynx was significantly higher ( 1 0.9%) than in cases with an associated cancer of the larynx or paranasal sinus (1.9%, p<0.05). All but one of the 37 cases detected by screening were asymptomatic and had superficial carcinoma. Of these lesions, 19 Were mucosal carcinomas, 17 submucosal carcinomas and only one an advanced cancer. Twenty-four of these 37 cases had died. The cause of death was head and neck cancer in 17, esophageal cancer in t w o and other causes in five. The 5-year survival rate of cases in whom the initial head and neck cancer had been treated curatively was 46.7%.The risk of synchronous esophageal cancer associated with cancer of the head and neck is high. Early detection of esophageal cancer at the time of diagnosing cancer of the head and neck and treatment at an early stage is a new strategy for improving the long-term outcome of cases with head and neck cancers associated with esophageal cancer. (Dig Endosc 1998 ; 10 : 110-1 15)

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Multiple Primary Cancers in Patients With Head and Neck Cancer and History of Tobacco Smoking and Drinking

Cited by 3 publications

References 8 publications

Four cases of simultaneous triple primary cancers of the hypopharynx, esophagus, and stomach

Four cases of simultaneous triple primary cancers of the hypopharynx, esophagus, and stomach

Second primary lung cancer after head and neck squamous cell cancer: Population‐based study of risk factors

Survival Benefit of Screening for Early Esophageal Carcinoma in Head and Neck Cancer Patients

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