Multiple recurrent myxofibrosarcoma of the orbit: case report and review of the literature

Abstract

Background Although myxofibrosarcoma (MFS) is the most common mesenchymal tumor, occurrence in the orbit is extremely rare. A characteristic clinical feature of MFS is its propensity for local recurrence (LR). Still, none of published literature has described the entire clinical course of multiple recurrences of MFS in the orbit. Here we present an unusual case in which a patient with multiple recurrences of MFS in the orbit followed-up for 5 years. We describe its clinical-pathological correlation, treatment, and prognosis. Case presentation A 70-year-old woman sought treatment for a year history of right upper eyelid swelling in May 2014. Since then, she underwent three surgical procedures in the right orbit in the same region (in 2014, 2016, and 2017). The pathology analysis of the three surgical tissue samples was consistent with myxofibrosarcoma, characterized by spindle-shaped cells and variably myxoid stroma. In the 2 years follow-up after the third surgery, there was no evidence of tumor recurrence. Conclusion Myxofibrosarcoma of the orbit is extremely rare. Since few reports are available in the literature, the diagnosis and management of the orbit myxofibrosarcoma is still a challenge to ophthalmologists. Histopathology is highly valuable in the diagnosis. As a clinical characteristic, the lesions have a high risk of local recurrence; therefore, aggressive resection and careful postoperative follow-up are paramount.

Emerging Atomic Layer Deposition Technology toward High‐k Gate Dielectrics, Energy, and Photocatalysis Applications

“…Moreover, the ALD coating strategy for solar cells in the photovoltaic field in the patent mainly includes the ALD dense TiO 2 electron transport layer in perovskite solar cells, [ 61 ] the silicon substrate output from the ALD coating device in heterojunction solar cells, [ 62 ] low‐cost back ALD passivation for high‐efficiency solar cells, etc. [ 63 ]…”