Multiple Sclerosis

Abstract

A compelling body of evidence suggests that hormones derived from the gonads, adrenals, pituitary, and other organs may profoundly affect multiple sclerosis (MS) susceptibility and severity. These hormones have powerful actions on elements of the immune system and also directly affect CNS recovery and resistance to injury. In addition, secretion of adrenal, gonadal, and pituitary hormones may be perturbed in MS with potentially important systemic consequences.Continuum Lifelong Learning Neurol 2009;15(2):148-178.