Multiple sclerosis-like neurological manifestations in a coeliac patient: nothing is as it seems

Abstract

Cobalamin (vitamin B₁₂) deficiency occurs with several disorders, involving different organs and systems, including blood, bowel, nervous system and eyes. Although the most important features are usually haematological ones, presence of neurological involvement, in the absence of blood count alterations, has just been described in the literature. Here we report the case of a 48-year-old man, suffering from coeliac disease for approximately 5 years, vegetarian, who was admitted to our department, referring dysaesthesia of the left lower limb, decreased libido and erectile dysfunction. Vitamin B₁₂ deficiency was proved, even in the absence of blood count alteration, and treated with a vitamin supplement, resulting in complete remission.

Sailing the ship of life: scurvy and autoimmunity . . .

“…Ciecierega et al 5 documented a rare co-existence of Hartnup disease in the setting of CD secondary to combined deficiencies in amino acids and proteins. Mansueto et al 6 reported a case of severe vitamin b12 deficiency resulting in multiple sclerosis like presentation secondary to underlying CD. A similar case of myelopathy was reported by Cavallieri et al 7 when severe copper deficiency resulted in a subacute combined degeneration presentation.…”

Нерешённые Проблемы И Перспективы Исследований Рассеянного Склероза: Вирусологические, Иммунологические И Терапевтические Аспект

“…К неифекционным болезням, имеющим сходные с РС клинико-инструментальные признаки, следует отнести антифосфолипидный синдром [55], нейроформу синдрома Шегрена [110], оптическую невропатию Лебера [70,117] (рис. 5), параинфекционные неврологические поражения [118], целиакию [73], полигландулярный аутоиммунный синдром [37], адренолейкодистрофию у Рис. 4.…”