Multiple solitary leiomyomata of the esophagus *

Torres, Antonio; Valladares, Luis Díez; Trancho, Florentino Hernando; Sánchez‐Pernaute, Andrés; Pérez-Aguirre, Elia; González, O.; Cantero, Ramón; Olmo, Alberto; Balibrea, J.L.

doi:10.1046/j.1442-2050.1999.00020.x

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…They can be distinguished histopathologically from diffuse leiomyomatosis, which is characterized by diffuse hypertrophy of the whole esophageal muscular layer, rather than the presence of discrete tumor nodules. 1,2 Although Seremetis et al 3 reported in a review of 838 leiomyoma cases that more than one tumor was occasionally found in the same patient (<2.4% of cases), more than three solitary lesions were not common. 3,4 The mechanism responsible for the development of multiple leiomyomas in the esophagus is unknown.…”

Section: Introductionmentioning

confidence: 94%

Multiple solitary leiomyomas in the esophagus: Report of a case

et al. 2011

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We herein report our findings for an asymptomatic 65-year-old man presenting with multiple solitary leiomyomas in the esophagus, who was undergoing follow-up for primary aldosteronism with high levels of serum progesterone. Esophageal endoscopy and computed tomography showed multiple submucosal tumors with calcification in the thoracic esophagus. A subtotal esophagectomy was performed because the possibility of malignancy could not be ruled out based on a needle biopsy taken of the specimen. The final resected specimen showed eight solitary, encapsulated nodules between the middle and lower thoracic esophagus. Histopathological examinations showed these nodules to have the typical histological findings of leiomyomas. In addition, staining with antibodies against the progesterone receptor revealed diffuse expression in the nuclei of the leiomyoma cells. Only four cases with more than eight solitary leiomyomas have been reported, including the current case. However, this is the first reported case where primary aldosteronism with elevated serum progesterone levels has been implicated in the pathogenesis of multiple solitary leiomyomas in the esophagus.

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Section: Introductionmentioning

confidence: 94%

Multiple solitary leiomyomas in the esophagus: Report of a case

et al. 2011

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“…Leiomyomas of esophagus are the most common esophageal mesenchymal tumors, by contrast, esophageal leiomyosarcomas are tumors that have been described anecdotally in medical literature [1]. We report two cases of leiomyosarcoma, which have been diagnosed by histopathology and immunohistochemistry (IHC) treated with different modalities.…”

Section: Introductionmentioning

confidence: 99%

A Leiomyosarcoma of Esophagus - Report of Two Cases

Reddy¹,

Narasimhan²,

Gunaraj³

et al. 2013

JCR

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Abstract:Leiomyosarcoma is a rare tumor of esophagus that accounts for 0.5% esophageal sarcomas. This paper presents two cases of leiomyosarcoma of esophagus in 45 years old lady and 52 years old gentleman who presented with dysphagia and they were evaluated to rule out malignancy, but they turned out to be rare leiomyosarcoma which were confirmed by immunohistochemistry. One patient underwent oesophagogastrectomy and other was treated with self-expandable metal stent (SEMS) in view of inoperability. Case presentations, diagnostic modalities and various management options are discussed.

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