Multiple variables influence the finely calibrated antioxidant defenses of
Clostridioides difficile
Erin B. Purcell
Abstract:The obligate anaerobe
Clostridioides difficile
encodes multiple reductases to detoxify molecular oxygen and reactive oxygen species. Caulat and colleagues have characterized the activity and regulation of four such reductases (L. C. Caulat, A. Lotoux, M. C. Martins, N. Kint, et al., mBio 15:e01591-24, 2024,
https://doi.org/10.1128/mbio.01591-24
). Each proved critical for clostridial survival in a different range of oxygen concentrations; together, they a… Show more
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