Multiplex aptamer cluster detection platform and systems toxicology study for 17β-estradiol, bisphenol A, and diethylstilbestrol

Li, Ning; Ren, Chenxi; Hu, Qin; Wang, Bo; Yang, Zhenquan; Xiao, Lixia; Guan, Tianzhu

doi:10.1016/j.foodchem.2024.141395

Food Chemistry

2025

DOI: 10.1016/j.foodchem.2024.141395

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Multiplex aptamer cluster detection platform and systems toxicology study for 17β-estradiol, bisphenol A, and diethylstilbestrol

Ning Li,

Chenxi Ren,

Qin Hu

et al.

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A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles

Rejab,

Dardouri,

Rouis

et al. 2024

Micromachines

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Bisphenol A (BPA) is a commonly synthetic chemical mainly used in producing plastic items. It is an endocrine-disrupting compound that causes irreversible health and environmental damage. Developing a simple method for BPA effective quantitative monitoring is emergently necessary. Herein, a novel electrochemical sensor for BPA detection based on [(5,10,15,20-tetrakis(p-bromophenyl) porphyrinato] cadmium (II) [(CdTBrPP)] and gold nanoparticle (AuNPs)-modified screen-printed carbon electrode (SPCE) was elaborated. CdTBrPP was synthesized and then characterized with Ultraviolet–Visible Spectroscopy (UV/vis), Infrared Spectroscopy (IR), and Proton Nuclear Magnetic Resonance Spectroscopy (1H NMR) to confirm its successful synthesis. After drop-coating AuNPs and CdTBrPP on the SPCE, the sensor performance was evaluated using square wave voltammetry (SWV), a linear response in a concentration range from 10−11 M to 10−2 M, with a low detection limit (LOD) of 9.5 pM. The CdTBrPP/AuNPs/SPCE sensor demonstrates a high selectivity and reproducibility, making it a promising candidate for developing a low-cost water-monitoring system for detecting BPA. Additionally, the proposed sensor effectively detected BPA in both tap and mineral water samples.

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A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles

Rejab,

Dardouri,

Rouis

et al. 2024

Micromachines

View full text Add to dashboard Cite

show abstract

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Multiplex aptamer cluster detection platform and systems toxicology study for 17β-estradiol, bisphenol A, and diethylstilbestrol

Cited by 1 publication

References 36 publications

A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles

A Selective Electrochemical Sensor for Bisphenol A Detection Based on Cadmium (II) (bromophenyl)porphyrin and Gold Nanoparticles

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