Multiplexed analysis of molecular and elemental ions using nanowire transistor sensors

Chen, Xi; Hu, Qitao; Chen, Si; Netzer, Nathan L.; Wang, Zhenqiang; Zhang, Shi-Li; Zhang, Zhen

doi:10.1016/j.snb.2018.05.018

Cited by 17 publications

(17 citation statements)

References 36 publications

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“…To achieve good accuracy, it was essential to choose an appropriate anionic site, as it affected selectivity as well as sensitivity [32,40,41]. We selected two different salts, namely, NaTFPB and KTClPB, widely used in recent works [42][43][44][45][46]. Considering that the extensive conditioning protocol is often disregarded in flexible film electrodes and wearable platforms, we provide the experiment results on using both salts after the same period of conditioning.…”

Section: Effect Of Membrane Ingredientmentioning

confidence: 99%

Wireless, Flexible, Ion-Selective Electrode System for Selective and Repeatable Detection of Sodium

Lim

Kim

Kwon

et al. 2020

Sensors

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Wireless, flexible, ion-selective electrodes (ISEs) are of great interest in the development of wearable health monitors and clinical systems. Existing film-based electrochemical sensors, however, still have practical limitations due to poor electrical contact and material–interfacial leakage. Here, we introduce a wireless, flexible film-based system with a highly selective, stable, and reliable sodium sensor. A flexible and hydrophobic composite with carbon black and soft elastomer serves as an ion-to-electron transducer offering cost efficiency, design simplicity, and long-term stability. The sensor package demonstrates repeatable analysis of selective sodium detection in saliva with good sensitivity (56.1 mV/decade), stability (0.53 mV/h), and selectivity coefficient of sodium against potassium (−3.0). The film ISEs have an additional membrane coating that provides reinforced stability for the sensor upon mechanical bending. Collectively, the comprehensive study of materials, surface chemistry, and sensor design in this work shows the potential of the wireless flexible sensor system for low-profile wearable applications.

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Section: Effect Of Membrane Ingredientmentioning

confidence: 99%

Wireless, Flexible, Ion-Selective Electrode System for Selective and Repeatable Detection of Sodium

Lim

Kim

Kwon

et al. 2020

Sensors

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“…Chen et al prepared a NW FET for the sensing of Na + and the methylene blue cation (MB + ). In this work, mixed-matrix membranes incorporating metal–organic supercontainer (MOSC) ionophores for Na + and MB + are decorated on Si NWs, and a multiplexer is employed for the analysis of river water.…”

Section: Semiconductor Nanowiresmentioning

confidence: 99%

“…In this work, mixed-matrix membranes incorporating metal–organic supercontainer (MOSC) ionophores for Na + and MB + are decorated on Si NWs, and a multiplexer is employed for the analysis of river water. This work is novel because it demonstrates the simultaneous and selective detection of molecular ions and simple metal ions in a single solution …”

Section: Semiconductor Nanowiresmentioning

confidence: 99%

“…The fabricated extended-gate devices showed a V th response of 50.9 mV/pH in the range from pH 3 to 11, which is superior to the performance of commercially available planar FET transducers with the same sensing area. 144 Chen et al 145 prepared a NW FET for the sensing of Na + and the methylene blue cation (MB + ). In this work, mixedmatrix membranes incorporating metal−organic supercontainer (MOSC) ionophores for Na + and MB + are decorated on Si NWs, and a multiplexer is employed for the analysis of river water.…”

Section: ■ Semiconductor Nanowiresmentioning

confidence: 99%

“…This work is novel because it demonstrates the simultaneous and selective detection of molecular ions and simple metal ions in a single solution. 145 Anand et al 146 used a bottom-up VLS process to fabricate multiple-parallel-connected (MPC) Si NW-FETs functionalized with DNA-aptamer for the detection of K + in cortical neuron efflux. In MPC Si NW-FETs, many Si NWs are trapped between the source and drain electrodes, leading to a cumulative response with a resulting enhancement in signal.…”

Section: ■ Semiconductor Nanowiresmentioning

confidence: 99%

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Sensors Based Upon Nanowires, Nanotubes, and Nanoribbons: 2016–2020

et al. 2020

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Abbreviations: LOD = limit of detection, BP = black phosphorus, NRs = nanoribbons, CNT = carbon nanotubes, AAO = anodic aluminum oxide, HT = hydrothermal synthesis, CVD = chemical vapor deposition, OTS = octadecyltrichlorosilane, DEP = dielectrophoresis, CR = chemiresistive, AM = amperometric, FET = field-effect transistor, AQP4 = aquaporin-4, HER2 = human epidermal growth factor receptor 2, PSA = prostatespecific antigen, NPY = neuropeptide Y, DHEAS = dehydroepiandrosterone sulfate, HCHO = formaldehyde, THC = tetrahydrocannabinol, N/A = information not available, and τ res / τ rec = reported or estimated response time/recovery time.

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Perspective of Printed Solid‐State Ion Sensors toward High Sensitivity and Selectivity

Bao

Kim

2020

Adv Eng Mater

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Ion‐selective field‐effect transistors (ISFETs) are integrated device systems with transistors and ion‐selective electrodes. The printed ISFET's sensing mechanisms are discussed. Then, different sensitive membranes linked with ISFETs are highlighted. To achieve high sensitivity and selectivity of ISFETs, various printing methods have been introduced recently. The real‐time monitoring sensing applications, such as ion detection in health, food safety, and environmental sectors, are discussed with the highlight on the biological applications for the cost‐efficient detection of DNA molecules. Finally, the challenges of the ISFETs are considered and illustrated with the proposed perspectives.

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Multiplexed analysis of molecular and elemental ions using nanowire transistor sensors

Cited by 17 publications

References 36 publications

Wireless, Flexible, Ion-Selective Electrode System for Selective and Repeatable Detection of Sodium

Wireless, Flexible, Ion-Selective Electrode System for Selective and Repeatable Detection of Sodium

Sensors Based Upon Nanowires, Nanotubes, and Nanoribbons: 2016–2020

Perspective of Printed Solid‐State Ion Sensors toward High Sensitivity and Selectivity

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