Multiplexing of Self and Other Information in Hippocampal Ensembles

Bos, Jeroen J.; Vinck, Martin; Marchesi, Pietro; Keestra, Amos; Jackson, Jadin C.; Verschure, Paul F. M. J.; Pennartz, Cyriel M. A.

doi:10.2139/ssrn.3398593

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We acknowledge the software tools provided by Kenneth Harris (University College London; Klustakwik), A. David Redish (University of Minnesota, Minneapolis; MClust), Michael Waskom and the Seaborn development team. The data is available on the EBRAINS platform (Bos, 2019), DOI: 10.25493/1PEP-K9F.…”

Section: Acknowledgementsmentioning

confidence: 99%

Hippocampal place cell sequences during a visual discrimination task: recapitulation of paths near the chosen reward site and independence from perirhinal activity

Marchesi,

Bos,

Vinck

et al. 2024

Preprint

View full text Add to dashboard Cite

Compressed hippocampal place-cell sequences have been associated with memory storage, retrieval and planning, but it remains unclear how they align with activity in the parahippocampal cortex. In a visuospatial discrimination task, we found a wide repertoire of hippocampal place cell sequences, which recapitulated paths across the task environment. Place cell sequences generated at reward sites predominantly reiterated trajectories near the chosen maze side, whereas trajectories associated with the side chosen in the previous trial were underrepresented. We hypothesized that neurons in the perirhinal cortex, which during the task display broad firing fields correlated with the animal's location, might reactivate in concert with hippocampal sequences. However, we found no evidence of significant perirhinal engagement during virtual trajectories, indicating that these hippocampal memory-related operations can occur independently of the perirhinal cortex.

show abstract

Section: Acknowledgementsmentioning

confidence: 99%