In underwater acoustic communication (UAC) systems, the channel characteristics are mainly affected by spatiotemporal changes, which are specifically manifested by two factors: the effects of refraction and scattering caused by seawater layered media on the sound field and the random fluctuations from the sea floor and surface. Due to the time-varying and space-varying characteristics of a channel, the communication signals have significant variations in time and space. Furthermore, the signal shows frequency-selective fading in the frequency domain and signal waveform distortion in the time domain, which seriously affect the performance of a UAC system. Techniques such as error correction coding or space diversity are usually adopted by UAC systems to neutralize or eliminate the effects of deep fading and signal distortion, which results in a significant waste of limited communication resources. From the perspective of the sound field, this study used experimental data to analyze the spatiotemporal fluctuation characteristics of the signal and noise fields and then summarized the temporal and spatial variation rules. The influence of the system then guided the parameter configuration and network protocol optimization of the underwater acoustic communication system by reasonably selecting the communication signal parameters, such as frequency, bandwidth, equipment deployment depth, and horizontal distance.