Multiresidue analysis of 15 antibiotics in honey using modified QuEChERS and high performance liquid chromatography-tandem mass spectrometry

Quantitative analysis of erythromycin, its major metabolite and clarithromycin in chicken tissues and eggs via QuEChERS extraction coupled with ultrahigh-performance liquid chromatography-tandem mass spectrometry

“…The sample preparation steps performed in this study were named protocol A, and other protocols (B, C and D) were revised based on these analytical methods ( Lan et al, 2019 , Xu et al, 2021 , Zhou et al, 2017 ). Protocols B, C and D described in the literature were implemented and tested for their suitability for the scope of this project and are discussed in Section 3.2.2 .…”

“…The principle of QuEChERS involves the adsorption of impurities through interactions between the adsorbent filler and the impurities in the matrix, thereby achieving the removal and purification of impurities ( Wang et al, 2021 ). Compared with the LLE and SPE methods, QuEChERS is inexpensive, consumes low levels of reagents, saves time, and achieves relatively high recovery and precision ( Xu et al, 2021 ). The combination of QuEChERS and liquid chromatography tandem mass spectrometry has been widely used in MAC residual analysis ( Campanharo et al, 2023 , Du et al, 2021 , de Mendonça Pereira et al, 2021 , Xu et al, 2021 ).…”

“…Compared with the LLE and SPE methods, QuEChERS is inexpensive, consumes low levels of reagents, saves time, and achieves relatively high recovery and precision ( Xu et al, 2021 ). The combination of QuEChERS and liquid chromatography tandem mass spectrometry has been widely used in MAC residual analysis ( Campanharo et al, 2023 , Du et al, 2021 , de Mendonça Pereira et al, 2021 , Xu et al, 2021 ). Du et al (2021) developed a QuEChERS method using multiwalled carbon nanotubes (MWCNTs) as the adsorbent, and 11 MACs in animal tissues and eggs were detected via ultrahigh-performance liquid chromatography tandem triple quadrupole mass spectrometry (UHPLC–MS/MS).…”

“…The QuEChERS-DLLME-HPLC–MS/MS method uses primary secondary amine (PSA) as an adsorbent and results in good recovery (103–110 %) and precision (4.5–6.3 %). Xu et al (2021) reported a QuEChERS-HPLC–MS/MS method for the analysis of 13 MACs and 2 lincosamides in honey. The effects of different adsorbents on antibiotic recovery in honey were compared through this method, and zinc oxide (ZnO) was successfully screened as an adsorbent.…”

A Novel Electrochemical Sensor for Chloramphenicol Based on MXenes and Carbon Nanofiber from Bacterial Cellulose

“…3 Therefore, many countries, such as the USA, Canada, and China, have prohibited the use of CAP in the production of food of animal origin. 4 Currently, the main detection methods for antibiotics are enzyme-linked immunosorbent assays, 5 high-performance liquid chromatography, 6 mass spectrometry, 7,8 and surface-enhanced Raman scattering. 9 Although these methods have high sensitivity and accuracy, they have certain shortcomings.…”