Multiresidue screening of pesticides in Panax Ginseng C. A. Meyer by ultra‐high‐performance liquid chromatography with quadrupole time‐of‐flight mass spectrometry

Abstract

In this study, an efficient screening method based on a modified quick, easy, cheap, effective, rugged, and safe extraction method combined with ultra‐high‐performance liquid chromatography coupled to tandem quadrupole time‐of‐flight mass spectrometry was established for the determination of 90 pesticides residues in Panax Ginseng. The accuracy of the method was then verified by analyzing the false positive rate and the screening detection limit in Ginseng. The results revealed that the screening detection limit of 33 of 90 pesticide residues were 0.01 mg·kg−1, 22 species were 0.05 mg·kg−1, 11 species were 0.10 mg·kg−1, 8 species were 0.20 mg·kg−1, and another 16 species were greater than 0.20 mg·kg−1. A total of 73 pesticides were ultimately suitable to be practically applied for rapid analysis of pesticide residues in Ginseng. Finally, the established method was used to analyze the pesticide residues in 35 Ginseng samples available on the market. And the residual of dimethomorph, azoxystrobin, tebuconazole, and pyraclostrobin was relatively severe in Ginseng samples. This work expanded the range of pesticides detected and provided a rapid, effective method for pesticides screening in Ginseng.

Application of Liquid Chromatography Coupled to Mass Spectrometry in Quality Assessment of Dietary Supplements—A Case Study of Tryptophan Supplements: Release Assay, Targeted and Untargeted Studies

“…Similarly, targeted screening for pesticides and mycotoxins (which were detected in herbal formulations), dioxins (detected in fish oil formulations), cyanobacterial neurotoxins (detected in shark cartilage) and microcystins (detected in algae) because they were not warranted, was not conducted in the study. For instance, pesticides were previously detected in supplements with Ginkgo [44,46] and Ginseng [47,48], whereas mycotoxins were in supplements with Ginkgo and grapes (Table A1). Many of these compounds require targeted screening as well as isolation and enrichment from the complex matrix to obtain a reliable signal [49].…”

Constituents, pharmacological activities, pharmacokinetic studies, clinical applications, and safety profile on the classical prescription Kaixinsan

“…Nevertheless, the clinical efficacy and safety of herbal medicine are also susceptible to being influenced by germplasm resources and growth conditions ( Ren et al, 2020 ). Pesticide residues in herbal medicine are one of the most important issues affecting safety ( Yue et al, 2022 ). More attention should be paid to the pesticide residues that may accumulate with long-term consumption of KSX.…”

Alien species water hyacinth realizes waste into treasure: The preparation of biomass sorbent to determine benzoylurea insecticides in tea products

“…The low concentration of BUs and complex matrix effects in real samples make it difficult to direct detection, and thus various sample pretreatment methods have been developed [5][6][7][8][9][10][11][12][13][14][15][16][17]. Among them, solid-phase extraction (SPE), including magnetic solid-phase extraction and solid-phase microextraction, is the most common pretreatment technique owing to their advantages of low solvent consumption, high enrichment factor, and easy automation.…”