Multiresistant clones of Salmonella enterica: The importance of dissemination

Davis, Margaret A.; Hancock, Dale D.; Besser, Thomas E.

doi:10.1067/mlc.2002.126411

Cited by 89 publications

(61 citation statements)

References 68 publications

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“…The prevalence of DT104 strains in house rats, demon- 7 90 1 2 B2-90-V1 21 B2-90-V2 2 85 1 2 B2-85-V1 21 B2-85-V2 2 80 1 2 B2-80-V1 21 B2-80-V2 2 75 0 1 B2-75-V1 24 95-B3 95 0 1 B3-95-V1 2 XbaI 95-B1 95 0 1 B1-95-X1 2 95-B2 95 2 1 B2-95-X1 20 90 1 1 B2-90-X1 21 85 1 1 B2-85-X1 21 80 0 1 B2-80-X1 22 95-B3 95 3 1 B3-95-X1 21 90 0 PROPERTIES OF SALMONELLA SEROVAR TYPHIMURIUM DT104 2627 strated in this study, supports the hypothesis of global expansion of DT104 by clonal dissemination (5,29). Generally, the increase in antibiotic-resistant bacteria is due to selective pressure by antibiotics (7,36).…”

Section: Discussionsupporting

confidence: 75%

Prevalence and Genetic Properties ofSalmonella entericaSerovar Typhimurium Definitive Phage Type 104 Isolated fromRattus norvegicusandRattus rattusHouse Rats in Yokohama City, Japan

Yokoyama

Maruyama

Kabeya

et al. 2007

Appl Environ Microbiol

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Salmonella enterica serovar Typhimurium was isolated from the intestinal contents of Rattus rattus and Rattus norvegicus house rats captured at two buildings, designated buildings J and YS, in Yokohama City, Japan. From October 1997 to September 1998, 52 of 339 (15.3%) house rats were found to carry Salmonella serovar Typhimurium definitive phage type 104 (DT104). In building J, 26 of 161 (16.1%) house rats carried DT104 over the 1-year study period, compared to 26 of 178 (14.6%) rats in building YS. The isolation rates of DT104 from R. rattus and R. norvegicus were similar in the two buildings. Most DT104 strains from building J (24 of 26) showed resistance to ampicillin, chloramphenicol, streptomycin, sulfisoxazole, and tetracycline and contained both the 1.0-and 1.2-kbp integrons, carrying genes pse1, pasppflo-like, aadA2, sulI, and tet(G). All DT104 strains from building YS were resistant to ampicillin and sulfisoxazole, and had the 1.2-kbp integron carrying pse1 and sulI. Cluster analysis of pulsed-field gel electrophoresis patterns of BlnI-digested DT104 DNAs showed that 22 of 26 DT104 strains from building J and 24 of 26 strains from building YS could be grouped into separate clusters each specific for the building origin. These results indicated that DT104 strains were prevalent in house rat colonies in each building and suggest that house rats may play an important role in the epidemiology of DT104.

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Section: Discussionsupporting

confidence: 75%

Prevalence and Genetic Properties ofSalmonella entericaSerovar Typhimurium Definitive Phage Type 104 Isolated fromRattus norvegicusandRattus rattusHouse Rats in Yokohama City, Japan

Yokoyama

Maruyama

Kabeya

et al. 2007

Appl Environ Microbiol

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“…Dissemination of antimicrobial resistance genes takes place at several scales (within bacterial populations through horizontal gene transmission and within and between hosts through clonal bacteria dissemination) and it is influenced by several factors, including selection pressures, genetic basis of resistance, mechanisms of genetic exchange, and fitness of the resistant organisms relative to the sensitive strains (Andersson and Hughes, 2010). An example of resistant bacteria transmission between hosts is the clonal MDR Salmonella Typhimurium definitive type 104, which emerged from an unknown location and was disseminated globally during the 1980s and 1990s (Davis et al, 2002). Within a host, bacteria acquire new antimicrobial resistance genes through horizontal gene transfer, with conjugative plasmids and transposons as the most common transmission vectors (Boerlin and ReidSmith, 2008).…”

Section: Modeling Antimicrobial Resistance Disseminationmentioning

confidence: 99%

Mathematical Modeling of the Transmission and Control of Foodborne Pathogens and Antimicrobial Resistance at Preharvest

Lanzas

Gröhn

2011

Foodborne Pathogens and Disease

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Foodborne diseases are a significant health-care and economic burden. Most foodborne pathogens are enteric pathogens harbored in the gastrointestinal tract of farm animals. Understanding the transmission of foodborne pathogens and the dissemination of antimicrobial resistance at the farm level is necessary to design effective control strategies at preharvest. Mathematical models improve our understanding of pathogen dynamics by providing a theoretical framework in which factors affecting transmission and control of the pathogens can be explicitly considered. In this review, we aim to present the principles underlying the mathematical modeling of foodborne pathogens and antimicrobial resistance at the farm level to a broader audience.

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“…Molecular typing studies have shown that this MR DT104 clone appeared simultaneously in the United Kingdom, Europe, and the United States during the mid-1980s (9). MR DT104 with the same resistance profile (ampicillin, chloramphenicol, streptomycin, sulfonamides, and tetracycline) had been isolated from humans in Asia prior to 1982 (22), but it is not currently known if these are identical to the globally disseminated clone.…”

mentioning

confidence: 99%

The Genomic Island SGI1, Containing the Multiple Antibiotic Resistance Region ofSalmonella entericaSerovar Typhimurium DT104 or Variants of It, Is Widely Distributed in OtherS. entericaSerovars

et al. 2005

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The global dissemination of the multiply-antibiotic-resistant Salmonella enterica serovar Typhimurium DT104 clone with the resistance genes located in a class 1 integron, here designated In104, within genomic island SGI1 is a significant public health issue. Here, we have shown that SGI1 and variants of it carrying different combinations of resistance genes are found in several Salmonella enterica serovars. These are serovars Cerro, Derby, Dusseldorf, Infantis, Kiambu, and Paratyphi B dT ؉ isolated from human infections and serovar Emek from sewage effluent. Two new variants, SGI1-I and SGI1-J, both of which include the dfrA1-orfC cassette array, were identified.

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Multiresistant clones of Salmonella enterica: The importance of dissemination

Cited by 89 publications

References 68 publications

Prevalence and Genetic Properties ofSalmonella entericaSerovar Typhimurium Definitive Phage Type 104 Isolated fromRattus norvegicusandRattus rattusHouse Rats in Yokohama City, Japan

Prevalence and Genetic Properties ofSalmonella entericaSerovar Typhimurium Definitive Phage Type 104 Isolated fromRattus norvegicusandRattus rattusHouse Rats in Yokohama City, Japan

Mathematical Modeling of the Transmission and Control of Foodborne Pathogens and Antimicrobial Resistance at Preharvest

The Genomic Island SGI1, Containing the Multiple Antibiotic Resistance Region ofSalmonella entericaSerovar Typhimurium DT104 or Variants of It, Is Widely Distributed in OtherS. entericaSerovars

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