2017
DOI: 10.3390/e19040145
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Multiscale Cross-Approximate Entropy Analysis of Bilateral Fingertips Photoplethysmographic Pulse Amplitudes among Middle-to-Old Aged Individuals with or without Type 2 Diabetes

Abstract: Abstract:Multiscale cross-approximate entropy (MC-ApEn) between two different physiological signals could evaluate cardiovascular health in diabetes. Whether MC-ApEn analysis between two similar signals such as photoplethysmographic (PPG) pulse amplitudes of bilateral fingertips can reflect diabetes status is unknown. From a middle-to-old-aged population free of prior cardiovascular disease, we selected the unaffected (no type 2 diabetes, n = 36), the well-controlled diabetes (glycated hemoglobin (HbA1c) <8%, … Show more

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Cited by 10 publications
(9 citation statements)
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“…We have previously shown that discrepancy in DVP waveform amplitude between two upper limbs can differentiate young from aged subjects and patients with good from those with poor diabetic control as well as identify arteriosclerosis risks 15 . Using the multiscale entropy approach, DVP waveform amplitudes have also been demonstrated to differentiate healthy from diabetic subjects 16 , 17 .…”
Section: Discussionmentioning
confidence: 99%
“…We have previously shown that discrepancy in DVP waveform amplitude between two upper limbs can differentiate young from aged subjects and patients with good from those with poor diabetic control as well as identify arteriosclerosis risks 15 . Using the multiscale entropy approach, DVP waveform amplitudes have also been demonstrated to differentiate healthy from diabetic subjects 16 , 17 .…”
Section: Discussionmentioning
confidence: 99%
“…The derivative operation of Equation (14) is processed to obtain the dual optimization problem as follows:…”
Section: Multiscale Dispersion Entropymentioning
confidence: 99%
“…However, AE is heavily relied on the data length. Moreover, its estimated value is uniformly lower than expected ones when processing the short dataset [14]. To overcome the weakness of AE, Richman and Moorman proposed sample entropy (SE) [15].…”
Section: Introductionmentioning
confidence: 98%
“…ApEn was proposed by Pincus [14,15] to quantitatively detect the regularity and complexity of various time series. Due to ApEn having the advantages of small amount of data, strong antinoise ability and accurate detection results, it has been widely used in the fields of medical treatment, stock markets, networks, meteorology and so on [16][17][18][19][20]. Sample entropy is an improved method of ApEn, which has great advantages in the abrupt analysis of hydrological series, but slightly lacks trend analysis for sequences [21].…”
Section: Introductionmentioning
confidence: 99%