Multiscale dynamics of interstimulus interval integration in visual cortex

Abstract

Although the visual cortex receives information at multiple temporal patterns, much of the research in the field has focused only on intervals shorter than 1 second. Consequently, there is almost no information on what happens at longer temporal intervals. We have tried to address this question recording neuronal populations of the primary visual cortex during visual stimulation with repetitive grating stimuli and intervals ranging from 1 to 7 seconds. Our results showed that firing rate and response stability were dependent of interval duration. In addition, there were collective oscillations with different properties in response to changes in intervals duration. These results suggest that visual cortex could encode visual information at several time scales using oscillations at multiple frequencies.

Time stability and connectivity analysis with an intracortical 96-channel microelectrode array inserted in human visual cortex

“…Microelectrode arrays, such as the Utah electrode array (UAE) which contains 100 penetrating microneedles, have been widely used to record and stimulate different brain areas [1][2][3]. The neural signals collected with UAEs inserted in the motor cortex have been successfully used to build brain-machine interfaces that decode motor intention and are able to control robotic platforms [4][5][6][7][8]; and in combination with functional electrical stimulation to control body parts in tetraplegic patients [9][10][11].…”