Multisensory integration after traumatic brain injury: a reaction time study between pairings of vision, touch and audition

Sarno, Stefania; Erasmus, Lutz-Peter; Lipp, Berthold; Schlaegel, Wolfgang

doi:10.1080/0269905031000070161

Cited by 35 publications

(22 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The sensory information can include any combination of auditory, visual, vestibular, tactile, proprioceptive, olfactory, and gustatory (taste) stimuli. Behavioral response to the events around us relies on the ability to integrate information from more than one sensory channel [1]. Therefore, deficits in processing or integrating sensory input during the developmental years can impact age-appropriate learning, attention, motor development, academic achievement, and family relationships [2,3].…”

Section: Introductionmentioning

confidence: 99%

Multisensory processing in children with cochlear implants

Bharadwaj

Matzke

Daniel³

2012

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Section: Introductionmentioning

confidence: 99%

Multisensory processing in children with cochlear implants

Bharadwaj

Matzke

Daniel³

2012

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

“…44,95 Sensory deficiencies and hyper-sensitivity have been reported in TBI patients. 35,36,[96][97][98] The P4 amelioration of hyper-sensitive to whisker stimulation may translate to reduced sensory sensitivity in people with severe TBI or reflect changes in anxiety, a factor in the whisker nuisance task. 44,95 This is consistent with reports of lower anxiety outcomes in TBI subjects treated with progesterone.…”

mentioning

confidence: 98%

Progesterone Exacerbates Short-Term Effects of Traumatic Brain Injury on Supragranular Responses in Sensory Cortex and Over-Excites Infragranular Responses in the Long Term

Allitt

Johnstone

Richards

et al. 2016

Journal of Neurotrauma

View full text Add to dashboard Cite

Progesterone (P4) has been suggested as a neuroprotective agent for traumatic brain injury (TBI) because it ameliorates many post-TBI sequelae. We examined the effects of P4 treatment on the short-term (4 days post-TBI) and long-term (8 weeks post-TBI) aftermath on neuronal processing in the rodent sensory cortex of impact acceleration-induced diffuse TBI. We have previously reported that in sensory cortex, diffuse TBI induces a short-term hypoexcitation that is greatest in the supragranular layers and decreases with depth, but a long-term hyperexcitation that is exclusive to the supragranular layers. Now, adult male TBI-treated rats administered P4 showed, in the short term, even greater suppression in neural responses in supragranular layers but a reversal of the TBI-induced suppression in granular and infragranular layers. In long-term TBI there were only inconsistent effects of P4 on the TBI-induced hyperexcitation in supragranular responses but infragranular responses, which were not affected by TBI alone, were elevated by P4 treatment. Intriguingly, the effects in the injured brain were almost identical to P4 effects in the normal brain, as seen in sham control animals treated with P4: in the short term, P4 effects in the normal brain were identical to those exercised in the injured brain and in the long term, P4 effects in the normal brain were rather similar to what was seen in the TBI brain. Overall, these results provide no support for any protective effects of P4 treatment on neuronal encoding in diffuse TBI, and this was reflected in sensorimotor and other behavior tasks also tested here. Additionally, the effects suggest that mechanisms used for P4 effects in the normal brain are also intact in the injured brain.

show abstract

“…Tools for assessing central processing again focus on a single sense. There is also evidence that TBI can cause deficits in multisensory integration [63], such as limitations in the way the brain processes and combines information from each sense and the environment to assemble a unified picture, which might be noted in a task requiring the combination of auditory information with the articulatory gestures of the lips and face to improve recognition of speech in a noisy environment [64]. Successful multimodal integration results in responses to multimodal stimuli that are faster than would be predicted from response times to single-sensory stimuli [65] and that produce larger neural responses than single-sense inputs [66].…”

Section: Assessmentmentioning

confidence: 99%

Blast exposure and dual sensory impairment: An evidence review and integrated rehabilitation approach

Saunders¹,

Echt²

2012

JRRD

View full text Add to dashboard Cite

Abstract-Combat exposures to blast can result in both peripheral damage to the ears and eyes and central damage to the auditory and visual processing areas in the brain. The functional effects of the latter include visual, auditory, and cognitive processing difficulties that manifest as deficits in attention, memory, and problem solving-symptoms similar to those seen in individuals with visual and auditory processing disorders. Coexisting damage to the auditory and visual system is referred to as dual sensory impairment (DSI). The number of Operation Iraqi Freedom/Operation Enduring Freedom Veterans with DSI is vast; yet currently no established models or guidelines exist for assessment, rehabilitation, or service-delivery practice. In this article, we review the current state of knowledge regarding blast exposure and DSI and outline the many unknowns in this area. Further, we propose a model for clinical assessment and rehabilitation of blast-related DSI that includes development of a coordinated team-based approach to target activity limitations and participation restrictions in order to enhance reintegration, recovery, and quality of life.

show abstract

Multisensory integration after traumatic brain injury: a reaction time study between pairings of vision, touch and audition

Cited by 35 publications

References 29 publications

Multisensory processing in children with cochlear implants

Multisensory processing in children with cochlear implants

Progesterone Exacerbates Short-Term Effects of Traumatic Brain Injury on Supragranular Responses in Sensory Cortex and Over-Excites Infragranular Responses in the Long Term

Blast exposure and dual sensory impairment: An evidence review and integrated rehabilitation approach

Contact Info

Product

Resources

About