Dermatosis, a kind of common and frequent disease, is harmful to health and risk against the lives of human beings. The detection of dermatosis is of great significance, especially to the early diagnosis of skin disease. Nowadays, the studies of spectral imaging technology in the diagnosis of skin disease are attracting more and more attentions. In this paper, we firstly review some literary products related to dermatosis detection and then make a comparison among fluorescence spectrum method, filter wheel method, liquid crystal tunable filter (LCTF) method and mosaic multispectral imaging technology. Finally we propose that the smaller, lighter and more cost-effective equipment should be the trend.