2023
DOI: 10.1038/s41398-023-02627-8
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Multivariate analyses of immune markers reveal increases in plasma EN-RAGE in first-episode psychosis patients

Laura Korhonen,
Elisabeth R. Paul,
Karin Wåhlén
et al.

Abstract: Immune cells and cytokines are largely recognized as significant factors in the pathophysiology of neuropsychiatric disorders. The possible role of other blood cells such as leukocytes in events of acute psychosis is in contrast only emerging. To study blood-born markers in acute psychosis we here evaluated plasma proteins in drug-naive first-episode psychosis (FEP) patients and healthy controls using a multiplex proximity extension assay technique. We analyzed a panel of 92 immune markers and plasma samples f… Show more

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