Multivariate analysis of risk factors for surgical site infection after laparoscopic colorectal surgery

Drosdeck, Joseph M.; Harzman, Alan; Suzo, Andrew; Arnold, Mark; Abdel-Rasoul, Mahmoud; Husain, Syed

doi:10.1007/s00464-013-3126-x

Cited by 52 publications

(35 citation statements)

References 23 publications

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“…In patients with mild or moderate hypertension, drugs used in chronic treatment may increase the need for active management of hypertensive episodes. Drosdeck et al24 reports that diabetes is a significant risk factor for incisional hernias. In contrast, no association between hypertension, diabetes, and postoperative morbidity early bowel obstruction is observed in another study 25.…”

Section: Discussionmentioning

confidence: 99%

Factors Influencing Difficulty of Laparoscopic Abdominoperineal Resection for Ultra-Low Rectal Cancer

Jiang

et al. 2017

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

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Purpose:Our current study was conducted to identify patients’ anatomic, pathologic, and clinical factors to predict difficulty of performing laparoscopic abdominoperineal resection for ultra-low rectal cancer.Materials and Methods:Records of 117 consecutive patients with rectal cancer 2 to 5 cm from the anal verge were retrospectively reviewed. Using univariate and multivariate linear or logistic regression models, standardized operative time and blood loss, as well as postoperative morbidity were utilized as endpoints to screen patients’ multiple variables to predict operative difficulty.Results:Multivariate linear regression analysis showed body mass index (BMI) (estimate=0.07, P=0.0056), interspinous distance (estimate=−0.02, P=0.0011), tumor distance from anal verge (estimate=−0.17, P=0.0355), prior abdominal surgery (estimate=0.51, P=0.0180), preoperative chemoradiotherapy (estimate=0.67, P=0.0146), and concurrent diseases (hypertension and/or diabetes mellitus) (estimate=0.49, P=0.0122) are predictors for standardized operative time. Age (estimate=0.02, P=0.0208) and concurrent diseases (estimate=0.43, P=0.0476) were factors related to standardized blood loss. BMI (estimate=0.15, P=0.0472) was the only predictor for postoperative morbidity based on logistic regression analysis.Conclusions:Age, BMI, interspinous distance, tumor distance from anal verge, prior abdominal surgery, preoperative chemoradiotherapy, and concurrent diseases influence the difficulty of performing laparoscopic abdominoperineal resection for ultra-low rectal cancer. Standardized operative time allows researchers to amass samples by pooling data from all published studies, thus building reliable models to predict operative difficulty for clinical use.

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Section: Discussionmentioning

confidence: 99%

Factors Influencing Difficulty of Laparoscopic Abdominoperineal Resection for Ultra-Low Rectal Cancer

Jiang

et al. 2017

Surgical Laparoscopy, Endoscopy &Amp; Percutaneous Techniques

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“…5 several small studies have shown a trend toward increased rates of ssi in iBD patients in relation to surgical approach, wound classification, and immunosuppressive state. [5][6][7][8][9] however, no multi-institutional study looking solely at the relationship between iBD and ssi has validated these findings.…”

mentioning

confidence: 81%

Increased Incidence of Surgical Site Infection in IBD Patients

Bhakta

Tafen

Glotzer

et al. 2016

Diseases of the Colon &Amp; Rectum

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“…Nonetheless, infection following operation remains a major factor affecting the morbidity of the patients, and surgical site infection (SSI) is particularly common following colorectal procedures, with reported rates ranging from 5-26 % [11][12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

Efficacy of perioperative synbiotics treatment for the prevention of surgical site infection after laparoscopic colorectal surgery: a randomized controlled trial

et al. 2015

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Multivariate analysis of risk factors for surgical site infection after laparoscopic colorectal surgery

Abstract: Alterations in surgical technique and specimen extraction site can reduce wound-related complications after laparoscopic colorectal resections. Remaining risk factors are largely nonmodifiable from a surgeon's perspective.

Cited by 52 publications

References 23 publications

Factors Influencing Difficulty of Laparoscopic Abdominoperineal Resection for Ultra-Low Rectal Cancer

Factors Influencing Difficulty of Laparoscopic Abdominoperineal Resection for Ultra-Low Rectal Cancer

Increased Incidence of Surgical Site Infection in IBD Patients

Efficacy of perioperative synbiotics treatment for the prevention of surgical site infection after laparoscopic colorectal surgery: a randomized controlled trial

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