Abstract. Blazars are high-energy engines providing us natural laboratories to study particle acceleration, relativistic plasma processes, magnetic field dynamics, black hole physics. Key informations are provided by observations at high-energy (in particular by Fermi/LAT) and very-high energy (by Cherenkov telescopes). I give a short account of the current status of the field, with particular emphasis on the theoretical challenges connected to the observed ultra-fast variability events and to the emission of flat spectrum radio quasars in the very high energy band.