Mumps is a relatively mild short-term viral infection of the salivary glands that usually occurs during childhood. Meningitis/encephalitis is a well-known complication of mumps, but involvement and infection of the testis in adolescent boys and adult men are rare. We report a case of an 18-year-old male patient with mumps associated epididymo-orchitis on the left side. The diagnosis was confirmed clinically and serologically by IgG and IgM titers. The symptoms were resolved after the administration of anti-inflammatory and pain medications with bed rest and ice packs applied to the area.