Mung bean seed coat water extract restores insulin sensitivity via upregulation of antioxidant defense system and downregulation of inflammation in insulin-resistant HepG2 cells

Pavasutti, Vipawanee; Sinthuvanich, Chomdao; Tayana, Ngampuk; Kongkiatpaiboon, Sumet; Sae-tan, Sudathip

doi:10.1016/j.nfs.2023.100145

Cited by 2 publications

(1 citation statement)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Then, the mixture was centrifuged at 3000 rpm for 10 min. The supernatant was collected and filtered through a syringe filter (0.45 µM) before the determination of the vitexin content using HPLC according to Pavasutti, Sinthuvanich et al (2023) [22]. Samples were subjected to HPLC equipped with a diode array detector (DAD) (Waters 600, Spectralab Scientific Inc., Milford, MA, USA).…”

Section: Preparation Of Vitexin-fermented Vegetablesmentioning

confidence: 99%

Potential Health Benefits of Fermented Vegetables with Additions of Lacticaseibacillus rhamnosus GG and Polyphenol Vitexin Based on Their Antioxidant Properties and Prohealth Profiles

Ngamsamer,

Muangnoi,

Tongkhao

et al. 2024

Foods

Self Cite

View full text Add to dashboard Cite

Fermented vegetables are increasingly being recognized as an important dietary component, particularly of plant-based diets, to achieve a sustainable healthy gut because of their microbial diversity and antioxidant properties. However, the functional relevance of fermented vegetables varies based on the raw ingredients used and nutrient supplementation. Therefore, in the present study, we investigated the microbial diversity and antioxidant activity of three formulas of fermented vegetables (standard, supplemented with Lacticaseibacillus rhamnosus GG, and supplemented with polyphenol vitexin) at days 0 and 15. The bacterial community profiles were determined through 16S rRNA sequencing analysis, and antioxidant activity was analyzed using 2,2-diphenyl-1-picrylhydrazyl and by measuring the oxygen radical absorbance capacity, the ferric reducing ability of plasma, and the total phenolic content. The results confirm microbial diversity in the taxonomic composition of the different formulas of fermented vegetables, with different bacteria predominating, particularly lactic acid bacteria including the genera Weissella, Pedicocccus, Leuconostoc, and Lactobacillus. Spearman’s correlation analysis showed significant differences in the specific bacteria present in the different formulas of fermented vegetables that conferred antioxidant capacity. Our findings show that supplementation with L. rhamnosus GG and polyphenol vitexin may effectively enhance the functional relevance of foods by promoting cellular protection against oxidative stress.

show abstract

Section: Preparation Of Vitexin-fermented Vegetablesmentioning

confidence: 99%

Potential Health Benefits of Fermented Vegetables with Additions of Lacticaseibacillus rhamnosus GG and Polyphenol Vitexin Based on Their Antioxidant Properties and Prohealth Profiles

Ngamsamer,

Muangnoi,

Tongkhao

et al. 2024

Foods

Self Cite

View full text Add to dashboard Cite

show abstract

Plant Extracts for Type 2 Diabetes: Mechanisms, Clinical Implications and Future Directions—A Systematic Review

Wang,

Liu,

2024

j biobased mat bioenergy

View full text Add to dashboard Cite

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease that is escalating globally and imposing a substantial burden on patients and society. Given the increasing prevalence of T2DM and the inadequacy of conventional therapeutic options, plant extracts have garnered significant attention as natural medicines. These extracts primarily encompass polyphenols, alkaloids, and polysaccharides. This review assesses the efficacy of these plant extracts in preventing and treating T2DM and its complications by collecting and analyzing relevant clinical trials and human studies to elucidate their mechanisms of action. Additionally, it highlights the role of plant extracts as adjunctive therapies in diabetes management while underscoring their promising applications in clinical practice. However, caution should be exercised due to potential risks associated with the use of plant extracts; further evaluation regarding their toxicities and interactions is warranted. We anticipate that our comprehensive review will offer improved treatment options for T2DM while inspiring advancements in botanical medicine.

show abstract

Mung bean seed coat water extract restores insulin sensitivity via upregulation of antioxidant defense system and downregulation of inflammation in insulin-resistant HepG2 cells

Cited by 2 publications

References 33 publications

Potential Health Benefits of Fermented Vegetables with Additions of Lacticaseibacillus rhamnosus GG and Polyphenol Vitexin Based on Their Antioxidant Properties and Prohealth Profiles

Potential Health Benefits of Fermented Vegetables with Additions of Lacticaseibacillus rhamnosus GG and Polyphenol Vitexin Based on Their Antioxidant Properties and Prohealth Profiles

Plant Extracts for Type 2 Diabetes: Mechanisms, Clinical Implications and Future Directions—A Systematic Review

Contact Info

Product

Resources

About