Muriel Sidnoma Ouédraogo, Nakougou Moϊ-Bohm Biatougou, Nomtondo Amina Ouédraogo, Angèle Ouangré/Ouédraogo, Gilbert Patrice Marie Louis Tapsoba, Adama Traoré, Fatimata Cissé, Nina Korsaga/Somé, Pascal Niamba, Jacques Simporé, Adama Traoré

Abstract

Kaposi’s sarcoma is a multifocal angiogenic tumor disease whose principal causal agent is human herpes virus 8 (HHV-8). Herein, we report a rare case of iatrogenic Kaposi’s sarcoma developing during oral corticotherapy. A 76-year-old, HIV-negative male presented with papulous, angiomatous lesions on the trunk and limbs, which appeared three months after the beginning of oral corticotherapy for bullous pemphigoid. We suspected iatrogenic Kaposi’s sarcoma given the time to lesion onset in relation to the immunosuppressive treatment, together with histological and virological confirmation of HHV-8. The lesions began to subside when corticosteroids were tapered down to 10 mg/day. This was the first case reported in our setting and it emphasized the need for the rigorous monitoring of patients receiving immunosuppressants to avoid overlooking the side effects or rare complications of these treatments. Key words: Kaposi’s sarcoma; Oral corticotherapy; HHV-8; Bullous pemphigoid

A strange umbilical rash in a newly diagnosed HIV-positive man: A new clinical description of a Trichosporon spp dermatosis

“…The clinical form of this fungus in our patient indicated a good therapeutic response to Penicillin G. However, previous studies have demonstrated positive antifungal activity with azoles and amphotericin B treatment for Trichosporon infection [5]. Other forms of treatment, such as the resection of the infected tissue, are associated with greater improvement [5,6].…”