Muscle, nerve, and skin biopsy

Indication for pediatric muscle biopsy determines usefulness

“…The intent of this procedure is to allow microscopic evaluation of structure and perform whole-tissue protein stains, mitochondrial genetic studies, ultrastructural analysis (ie, electron microscopy), and electron transport chain assays [2]. These procedures are generally conducted on an outpatient basis, but considerable pain and significant scarring can result.…”

Diagnostische Schritte bei Polyneuropathien: Neurophysiologie, Labordiagnostik, Biopsie

“…Die Sensitivität bei entzündlichen Neuropathien ist jedoch gering [62]. Die Suralis-Biopsie wird daher auch in den kommenden Jahren kaum zu ersetzen sein.…”