Muscle strength is the main associated factor of physical performance in older adults with knee osteoarthritis regardless of radiographic severity

Association of Thigh Muscle Strength With Knee Symptoms and Radiographic Disease Stage of Osteoarthritis: Data From the Osteoarthritis Initiative

“…Further, an effect of leg dominance on thigh muscle strength was not supported by the findings of Ditroilo et al (42). It has been reported previously that thigh muscle weakness affects gait (43) and knee function (44) and is an important determinant of functional disability (45,46). The current results are suggestive of thigh muscle weakness being caused by pain but not by radiographic changes per se (47).…”

Muscle Function during Selected Weight-Bearing Activities in Adults with Knee Osteoarthritis- A Narrative Overview

“…Furthermore, in light of the great variation of adaptive muscle activation patterns found among and within the muscles of adults with varying degrees of knee osteoarthritis,for example, the lateral knee muscle sites in one study were deemed reflective of the progression along the continuum from asymptomatic to severe osteoarthritis, whereas the medial muscle site measures differentiated severity between osteoarthritic groups [41] , it is presently impossible to outline or formulate any global theory about how muscles around the knee contribute directly or indirectly to knee joint osteoarthritis as outlined by Shull et al [32] . In addition to the aforementioned observations, muscle power [42] , and eccentric rather than concentric muscle coactivation [43] , as well as pain and a variety of muscular abnormalities may accompany osteoarthritic joint damage [47][48][49][50] , and/or may independently or collectively heighten activity limitations and central nervous system responses that foster the development of the disease [51][52][53] , but these factors have not commonly been examined in the context of the studies reported here. This is surprising given that subjects with knee osteoarthritis do present with significant muscle impairments that affect physical function [54] as well as wide variations in whole muscle contractile kinetics [55] .…”

Is Radiographic Severity of Knee Osteoarthritis Important for Detecting Differences in Physical Performance and Isokinetic Strength?

“…Radyolojik OA şiddeti arttıkça fiziksel fonksiyonun azaldığı vurgulanmaktadır (11)(12)(13). Dizin fiziksel fonksiyonu beden ağırlı-ğı (14), hareket açıklığı (15), kas aktivasyonu ve propriosepsiyon (4) gibi nöromuskuloskeletal faktörlerle belirlenir.…”

“…Dizin fiziksel fonksiyonu beden ağırlı-ğı (14), hareket açıklığı (15), kas aktivasyonu ve propriosepsiyon (4) gibi nöromuskuloskeletal faktörlerle belirlenir. Yaşlı bireylerde, radyolojik OA şiddetine bağımlı olmaksızın fiziksel fonksiyonu belirleyen temel faktörün kas kuvveti olduğu belirtilmekte (11), kas kuvvetindeki azalmanın diz osteoartritini ilerletmekten ziyade insidansı ile ilişkili olduğu vurgulanmaktadır (6). Yani radyolojik OA şiddeti ileri düzeyde olsa bile, kas kuvveti iyi olduğu takdirde fiziksel fonksiyonun korunduğu bildirilmektedir (11).…”

“…Şiddetli ve hafif derecede OA olan kadın ve erkeklerin fiziksel fonksiyon ve kuvvetini karşılaştıran az sayıda çalışma vardır (11,12). Bu çalışmalarda fiziksel fonksiyon, denge, otur kalk süresi, 4 metre (11) ve 15 metre yürüme süresi, basamak çık-ma (12) gibi zaman temelli performans testleri, Western Ontario and McMaster Universities Osteoarthritis İndeks (WOMAC) (10,11) ile ve kuvvet 60 0 /s hızda izokinetik testle (12) belirlenmiştir.…”