Musculoskeletal disorders of the hand in type 2 diabetes mellitus: prevalence and its associated factors

Abstract

Aim: To assess the prevalence of musculoskeletal disorders of the hand among adult patients with type 2 diabetes mellitus (T2DM) and their relation to disease duration, glycemic control and microvascular complications.Methods: A cross-sectional study was conducted at the National Center for Diabetes, Endocrinology and Genetics in Amman, Jordan.Results: One thousand patients with T2DM were included in this study (mean age 57.8 AE 9.5 years, 52.2% females and 47.8% males). Hand disorders were seen in 69.5% of patients, limited joint mobility (LJM) was the most prevalent (63.1%) condition followed by Dupuytren's contracture (DC) (18.6%). Trigger finger, thick skin and carpal tunnel syndrome (CTS) were found in 7.2%, 6.2% and 5.5% of patients, respectively. One disorder was seen in 45.4% of patients, two in18.2%, three in 4.9%, four in 0.9%, while only 0.1% of patients had all disorders. Female gender, age over 60 years and long duration of diabetes were associated with hand abnormalities. Hypertension was significantly associated with DC while retinopathy was associated with increased odds of thick skin, DC and CTS with P-values 0.037, < 0.005 and 0.002, respectively. Conclusion:Hand disorders are very common in T2DM. Female gender, old age, duration of diabetes, retinopathy and hypertension were significantly associated with hand disorders in T2DM.

Predictors of Outcomes Following Fasciectomy for Dupuytren’s Disease in Diabetic and Non-Diabetic Patients

“…14,15) Most of the extant literature evaluates the prevalence of Dupuytren's disease among patients with DM, but does not examine the surgical outcomes in this patient population. [1][2][3]6,16,17) In order to address this void, the objectives of the current study were to compare clinical outcomes, and identify predictors thereof, after palmar fasciectomy for Dupuytren's disease in diabetic patients compared with non-diabetic patients.…”

Relationship of shoulder activity and skin intrinsic fluorescence with low level shoulder pain and disability in people with type 2 diabetes

“…People with diabetes have a high incidence of musculoskeletal disorders and pain compared to those without diabetes (Larkin et al, 2014; Mustafa, Khader, Bsoul, & Ajlouni, 2015). These musculoskeletal problems have been particularly well documented in the shoulders and upper extremities and have been associated with other diabetic complications including nephropathy, retinopathy, coronary heart and cerebrovascular diseases (Arkkila, Kantola, & Viikari, 1997; Balci, Balci, & Tuzuner, 1999; Rosenbloom AI, Silverstein J, Lezotte DC, Richardson K, & McCallum M, 1981).…”

Tendinosis in Trigger Finger

“…The presented numbers (incidence, life time incidence, prevalence, period prevalence) however, vary widely, from 1.5% to 11.6% 108,111,[178][179][180][181][182] (among younger persons, 5% (14-38 years) 183 ) and there is no firm evidence concerning the risk 184 . The considerable range in incidence and prevalence has been suggested to be due to an ethnic component 178 .…”

“…The lowest number is from a large cohort study in California 111 with no registration of ethnicity. The highest number is from India 181 , and in between are studies from Jordan 179 , Iran 180 and Pakistan 178 . The studies differ considerably regarding methodology, and perhaps that is the reason for the discrepancy between studies.…”

“…The risk of trigger finger in diabetes is associated with high HbA1c 111 , neuropathy, nephropathy and retinopathy 181 , female gender, age over 60 years, long duration of diabetes and hypertension 179 , and the risk for multiple trigger fingers and bilateral involvement is increased 177 . A suggested explanatory model is irreversible glycosylation of collagen.…”