PID is a significant public health issue among sexually active women, with silent PID being a major diagnostic and treatment challenge. A 2008 study estimated an average direct medical cost of $3,202 per case of PID. A quantitative, cross-sectional, descriptive study was conducted to assess the factors influencing the prevalence of PID among sexually active women attending OBS/GYN clinics at KIU-TH. The study found that 45.6% of sexually active women at KIU-TH had PID, with 80.6% having their first intercourse at 18 years of age, 19.4% starting between 15-18 years, and 90.6% preferring pills or withdrawal for contraception. 51.9% attended government healthcare, while 56.2% used government facilities. Most PID patients reached within one hour or less than 30 minutes. Only 38.7% could meet their bills without insurance. Most patients agreed that health sensitization is essential, and 96.9% received counseling and professional advice. 62.5% of PID affected women were under 35 years old, 35.5% were unemployed, and 59.3% earned ≤50,000/= and had secondary education. The prevalence of PID among sexually active women at KIUTH is 45.6%. Keywords: prevalence, pelvic inflammatory disease, sexually active women