Mushroom Poisoning Cases in Dogs and Cats

Puschner, Birgit; Wegenast, Colette

doi:10.1016/j.cvsm.2018.06.008

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Psilocybin Mushrooms1

Detection Of Amatoxins In Dog Urine Samples1

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2020

2024

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Cited by 10 publications

(2 citation statements)

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“…Clinical signs which have been observed in dogs include ataxia, vocalization, overt aggression, increase in body temperature and nystagmus ( Kirwan, 1990 ; Puschner, 2018 ). Although clinical signs usually occur within 0.5–1 hour, rarely they can be delayed up to 3 h after ingestion ( Puschner & Wegenast, 2018 ).…”

Section: Psilocybin Mushroomsmentioning

confidence: 99%

Intoxication of dogs and cats with common stimulating, hallucinogenic and dissociative recreational drugs

Oster

Čudina

Pavasović

et al. 2023

Veterinary and Animal Science

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Section: Psilocybin Mushroomsmentioning

confidence: 99%

Intoxication of dogs and cats with common stimulating, hallucinogenic and dissociative recreational drugs

Oster

Čudina

Pavasović

et al. 2023

Veterinary and Animal Science

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“…Unfortunately, many dogs each year are poisoned by amatoxins due to their natural curiosity and indiscriminate eating habits [30,31]. To evaluate this LFIA for diagnostic potential, we collaboratively analyzed samples submitted to the California Animal Health and Food Safety Laboratory in Davis, CA, USA (CAHFS Davis).…”

Section: Detection Of Amatoxins In Dog Urine Samplesmentioning

confidence: 99%

Rapid, Sensitive, and Accurate Point-of-Care Detection of Lethal Amatoxins in Urine

Bever

Swanson

Hamelin

et al. 2020

Toxins

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Globally, mushroom poisonings cause about 100 human deaths each year, with thousands of people requiring medical assistance. Dogs are also susceptible to mushroom poisonings and require medical assistance. Cyclopeptides, and more specifically amanitins (or amatoxins, here), are the mushroom poison that causes the majority of these deaths. Current methods (predominantly chromatographic, as well as antibody-based) of detecting amatoxins are time-consuming and require expensive equipment. In this work, we demonstrate the utility of the lateral flow immunoassay (LFIA) for the rapid detection of amatoxins in urine samples. The LFIA detects as little as 10 ng/mL of α-amanitin (α-AMA) or γ-AMA, and 100 ng/mL of β-AMA in urine matrices. To demonstrate application of this LFIA for urine analysis, this study examined fortified human urine samples and urine collected from exposed dogs. Urine is sampled directly without the need for any pretreatment, detection from urine is completed in 10 min, and the results are read by eye, without the need for specialized equipment. Analysis of both fortified human urine samples and urine samples collected from intoxicated dogs using the LFIA correlated well with liquid chromatography–mass spectrometry (LC-MS) methods.

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Mushrooms, muscarine

Wiegand

2024

Encyclopedia of Toxicology

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Mushroom Poisoning Cases in Dogs and Cats

Cited by 10 publications

References 32 publications

Intoxication of dogs and cats with common stimulating, hallucinogenic and dissociative recreational drugs

Intoxication of dogs and cats with common stimulating, hallucinogenic and dissociative recreational drugs

Rapid, Sensitive, and Accurate Point-of-Care Detection of Lethal Amatoxins in Urine

Mushrooms, muscarine

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