Mushroom Poisoning Mimicking Painless Progressive Jaundice: A Case Report with Review of the Literature

Perisetti, Abhilash; Raghavapuram, Saikiran; Sheikh, Abu Baker; Rahman, Rubayat; Shanshal, Mohamed; Thein, Kyaw Zin; Farooq, Asif

doi:10.7759/cureus.2436

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…Although it is known that poisoning can lead to leukocytosis, the effects of other complete blood count parameters are not clear. 8,9 NLR has emerged as a frequently searched, cheap, and easy-to-use test in recent years.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of complete blood count parameters, cell ratios, and cell volume indices in mushroom poisonings

Doğan

Karahan

2019

Hum Exp Toxicol

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Objective: Mushroom poisoning is still a significant health-care problem, with the potential to affect blood parameters. The present study analyses the effect of mushroom poisoning on complete blood cell parameters, cell ratios, and cell volume indices and the effect of the mentioned parameters on prognosis/hospital length of stay. Methods: The study involved the retrospective assessment of 48 patients who became symptomatic after ingesting mushrooms. Patients who were 18 years and above and who spent at least one day in hospital were included in the study. The control group comprised individuals with similar characteristics to the patient group. The complete blood cell parameters, platelet indices (mean platelet volume, plateletcrit (PCT)), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio levels were compared between the two groups, and these ratios were analyzed for any correlation with length of hospital stay. Results: NLR was significantly higher and PCT was significantly lower in the mushroom-poisoned group, while all other parameters were similar between the groups. NLR had a positive correlation and PCT had a negative correlation with length of hospital stay. Conclusion: NLR and PCT levels can provide information about prognosis and can aid in the prediction of hospital stay in mushroom-poisoned patients. Further investigations are needed to investigate effects of intoxication on hematological system elements.

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Section: Discussionmentioning

confidence: 99%

Evaluation of complete blood count parameters, cell ratios, and cell volume indices in mushroom poisonings

Doğan

Karahan

2019

Hum Exp Toxicol

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Lactate and blood ammonia on admission as biomarkers to predict the prognosis of patients with acute mushroom poisoning and liver failure: a retrospective study

Gao

Hongqiao

Zhong

et al. 2021

Toxicology Research

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The diagnosis of liver damage induced by mushroom poisoning is still challenging. This study aims to screen the early biological indexes that could predict acute mushroom poisoning with liver damage. The patients with acute mushroom poisoning and liver damage admitted to The First Affiliated Hospital of Dalian Medical University，China from July 2007 to August 2017 were analyzed retrospectively. A total of 66 patients were enrolled in this study, with 44 and 22 patients in the liver injury group and liver failure group, respectively. Ten patients in the liver failure group died, with a mortality of 45.5% in this group. Multivariable Cox regression showed that the blood ammonia (NH3) and lactic acid (Lac) at the time of admission were independently associated with the in-hospital time to death for patients with liver failure induced by mushroom poisoning. Lactate and blood ammonia at the time of admission could be used to predict the prognosis of patients with acute mushroom poisoning and liver failure.

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Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements

Perisetti

Goyal

Thandassery

et al. 2021

WJG

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Primary liver cancers carry significant morbidity and mortality. Hepatocellular carcinoma (HCC) develops within the hepatic parenchyma and is the most common malignancy originating from the liver. Although 80% of HCCs develop within background cirrhosis, 20% may arise in a non-cirrhotic milieu and are referred to non-cirrhotic-HCC (NCHCC). NCHCC is often diagnosed late due to lack of surveillance. In addition, the rising prevalence of non-alcoholic fatty liver disease and diabetes mellitus have increased the risk of developing HCC on non-cirrhotic patients. Viral infections such as chronic Hepatitis B and less often chronic hepatitis C with advance fibrosis are associated with NCHCC. NCHCC individuals may have Hepatitis B core antibodies and occult HBV infection, signifying the role of Hepatitis B infection in NCHCC. Given the effectiveness of current antiviral therapies, surgical techniques and locoregional treatment options, nowadays such patients have more options and potential for cure. However, these lesions need early identification with diagnostic models and multiple surveillance strategies to improve overall outcomes. Better understanding of the NCHCC risk factors, tumorigenesis, diagnostic tools and treatment options are critical to improving prognosis and overall outcomes on these patients. In this review, we aim to discuss NCHCC epidemiology, risk factors, and pathogenesis, and elaborate on NCHCC diagnosis and treatment strategies.

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Mushroom Poisoning Mimicking Painless Progressive Jaundice: A Case Report with Review of the Literature

Cited by 3 publications

References 15 publications

Evaluation of complete blood count parameters, cell ratios, and cell volume indices in mushroom poisonings

Evaluation of complete blood count parameters, cell ratios, and cell volume indices in mushroom poisonings

Lactate and blood ammonia on admission as biomarkers to predict the prognosis of patients with acute mushroom poisoning and liver failure: a retrospective study

Non-cirrhotic hepatocellular carcinoma in chronic viral hepatitis: Current insights and advancements

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