Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

Abstract

Mushrooms have a significant role in human diet as functional food and as a nutraceutical resource. The combination of its umami flavor, protein, vitamins, minerals and carbohydrates has meant that mushrooms could be considered a cheap food source for a long time in many countries. Moreover, mushrooms contain an excellent variety of bioactive metabolites that can be successful in both prevention and treatment of various human health hazards. In addition, extracts from medicinal mushrooms and their metabolites have been verified for wound treating with contribution to different mechanisms of the healing process. This review summarizes the nutritional value and composition of mushrooms, ethnobiology and ethnopharmacology, and wound healing potential.

Curcumin nanoformulations for antimicrobial and wound healing purposes

“…Nature may bring us components with wound healing properties (J. Sharifi-Rad, Butnariu, et al, 2020) but technology and investigation are needed to improve these properties. Therefore, in the present review, we focused our attention on the antimicrobial and wound healing properties of nanoformulated curcumin, and we gave a perspective on its therapeutic applications for both microbial infections treatment and in the wound healing process.…”

“…However, curcumin low aqueous solubility, poor tissue absorption and low bioavailability is a problem which need to be solved through the design of new drug formulations such as curcumin nanoformulations (Kesharwani, Jain, Srivastava, & Keshari, 2020; C. Mohanty & Sahoo, 2017; J. Sharifi‐Rad, El Rayess, et al, 2020). Nature may bring us components with wound healing properties (J. Sharifi‐Rad, Butnariu, et al, 2020) but technology and investigation are needed to improve these properties. Therefore, in the present review, we focused our attention on the antimicrobial and wound healing properties of nanoformulated curcumin, and we gave a perspective on its therapeutic applications for both microbial infections treatment and in the wound healing process.…”

Hepatoprotective Effect of Ganoderma applanatum Crude Polysaccharides on Carbon Tetrachloride-Induced Early Liver Fibrosis in Mice

“…The nutrition works in accelerate body metabolism to dispose many toxins from the body. 30 Decreasing in liver weight and liver index explained that GACP play role in liver mass via decreasing collagen component which increase the weight of liver. 31 In this study, the degree of liver injury was indicated by measuring the levels of liver enzyme biomarkers.…”

Fungal exopolysaccharides: Properties, sources, modifications, and biomedical applications

“…The high capacity of the EPSs to capture and release its cargo, such as drugs and proteins, is one of the essential EPSs applications in EPSs-based hydrogels. Nielsen, 2013;Sharifi-Rad et al, 2020). βGs improve wound repair by promoting macrophages infiltration, which motivates tissue granulation, types I and III collagen, and re-epithelialization.…”