Throughout human history, music has been an important tool contributing to both the expression of feelings and healing. Today, its application is quite wide in both non-clinical and clinical populations. The subject of the paper is a presentation of the history, development, and definitions of music as an intervention, music therapy, and the benefits of its application in children, adolescents, the geriatric population, stress reduction, psychotherapy, the treatment of neurological disorders, and pain therapy. In order to analyze the benefits of applying music as an intervention, a literature review was done. In addition, musical interventions were divided into diagnostic and preventive. It can be concluded that with the established research and clinical paradigms and taking into account the limitations of previous studies, a scientific basis for further academic research is provided. Additional guidelines for more intensive and beneficial incorporation of musical interventions in the previously mentioned areas were provided.