Musical auditory stimulus acutely influences heart rate dynamic responses to medication in subjects with well-controlled hypertension

Abstract

Music can improve the efficiency of medical treatment when correctly associated with drug action, reducing risk factors involving deteriorating cardiac function. We evaluated the effect of musical auditory stimulus associated with anti-hypertensive medication on heart rate (HR) autonomic control in hypertensive subjects. We evaluated 37 well-controlled hypertensive patients designated for anti-hypertensive medication. Heart rate variability (HRV) was calculated from the HR monitor recordings of two different, randomly sorted protocols (control and music) on two separate days. Patients were examined in a resting condition 10 minutes before medication and 20 minutes, 40 minutes and 60 minutes after oral medication. Music was played throughout the 60 minutes after medication with the same intensity for all subjects in the music protocol. We noted analogous response of systolic and diastolic arterial pressure in both protocols. HR decreased 60 minutes after medication in the music protocol while it remained unchanged in the control protocol. The effects of anti-hypertensive medication on SDNN (Standard deviation of all normal RR intervals), LF (low frequency, nu), HF (high frequency, nu) and alpha-1 scale were more intense in the music protocol. In conclusion, musical auditory stimulus increased HR autonomic responses to anti-hypertensive medication in well-controlled hypertensive subjects.

The effects of musical auditory stimulation on heart rate autonomic responses to driving: A prospective randomized case-control pilot study

“…Conversely, this study did not elucidate whether classical music elicited significant relaxant effects (F. M. Vanderlei, de Abreu, Garner, & Valenti, 2016). Additionally, contemporary music was able to improve the effects of antihypertensive medication on HRV in well-controlled hypertensive subjects (Martiniano et al, 2018). This study stated that music styles written by Adele, Electra, Chris Tomlin and Enya positively influenced HR autonomic responses induced by anti-hypertensive medication.…”

“…So, we planned to assess the acute effects of auditory stimulation with contemporary music on HR autonomic control during driving under intense urban traffic conditions. We were concerned in testing a specific music program applied in a previous study that provided positive effects on HRV in hypertensive subjects (Martiniano et al, 2018) and we expect that this specially-selected music program helped attain this level.…”

Involvement of birth weight and body composition on autonomic recovery following aerobic exercise in children: A prospective, observational and analytical study

“…HRV analysis followed directives from the Task Force 36 and have been previously published [37,38]. Kubios HRV ® software (Kubios ® HRV v.1.1 for Windows, Biomedical Signal Analysis Group, Department of Applied Physics, University of Kuopio, Finland) was necessary to calculate linear indices.…”

Waist-Stature Ratio And Its Relationship With Autonomic Recovery From Aerobic Exercise In Healthy Men

“…This counting method for RR intervals followed directives from the Task Force 12 , 24 and were before now published in previous studies 25 – 28 .…”