The fusion of emerging technology, means, and music has provided a diversified development direction for the performance form of electronic music. Interactive electronic music has become a hot form of music performance in recent years and is widely used in various art exhibitions. In this paper, we will briefly explain the basic principles and practical applications of wireless wearable sensing devices, sort out the development of interactive platforms and sensors, and study the application value of wireless wearable sensing devices in interactive electronic music works. Near-field communication (NFC), as a short-range radio technology, can realize wireless energy and data transmission simultaneously. By integrating NFC modules, electrochemical sensing circuits, and flexible electrodes, it is possible to ensure complete electrochemical sensing functions while maximizing the miniaturization, flexibility, and integration of the system. Therefore, this paper constructs a series of wireless passive flexible electrochemical sensing systems based on NFC technology, electrochemical sensing technology, and flexible electronics, and uses these systems to realize a series of innovative applications, aiming to guide the creation of higher quality interactive music artworks as well as explore the artistic and esthetic experience brought by interactive music functions, and provide theoretical references for virtual art interactive music creation and practice.