Mutagenicity of anthraquinone and azo dyes in Ames' Salmonella typhimurium test

Venturini, S.; Tamaro, M.

doi:10.1016/0165-1218(79)90163-0

Cited by 52 publications

(12 citation statements)

References 12 publications

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“…Liberman et al [86] reported that chrysophanol and islanding mycotoxins (Table 1, Compounds 27 and 45) produced by Penicillium islandicum are frameshift mutagens which require metabolic activation (S9). The mutagenic activity associated with these two mycotoxins is quantitatively different from that observed with emodin, a known mutagenic mycotoxin for TA1537 [85].…”

Section: Mutagenic Activitymentioning

confidence: 80%

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Structure Antimutagenicity Relationship of Anthraquinones

Mohammed¹

2016

Nat Prod Chem Res

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Naturally occurring anti-mutagenic principles present in plants, human diet and other sources have protective effects against mutagens. Anthraquinones (AQs) considered one of the major plant phenolic pigments that contain many members, have evidenced the capability for inhibiting the mutagenicity toward Salmonella typhimurium of a number of mutagens. Not only genotoxicity/carcinogenesis is caused by mutagens but also the inception and pathogenesis of several chronic degenerative diseases. The present review attempts to furnish a brief overview on structure-antimutagenicity relationships of natural and synthetic anthraquinones.

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Section: Mutagenic Activitymentioning

confidence: 80%

“…Many natural and synthetic hydroxy-, amino-, nitro-and benzAQs are mutagenic in the Ames/Salmonella assay [69,85,86]. The majority of these AQs are classified as frameshift mutagens (those cause insertion or deletions of a number of nucleotides in a DNA sequence) due to their reactivity toward Ames strains TA1537, TA1538 or TA98.…”

Section: Mutagenic Activitymentioning

confidence: 99%

Structure Antimutagenicity Relationship of Anthraquinones

Mohammed¹

2016

Nat Prod Chem Res

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“…These observations are in accordance with several studies that report mutagenicity of a number of dyes like Direct Black 38, Acid Red 26, etc. [4,19]. Unlimited and uncontrolled use of such dyes can lead to grave consequences in terms of human health and ecological balance.…”

Section: Resultsmentioning

confidence: 99%

“…Pali is an important district of Rajasthan, having a population of 18,19,201 people. It is situated about 70 kms from Jodhpur.…”

Section: Introductionmentioning

confidence: 99%

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Assessing Mutagenicity of Textile Dyes From Pali (Rajasthan) Using Ames Bioassay

Mathur¹

2006

Appl Ecol Env Res

150

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Abstract. In Rajasthan state particularly, textile mills represent an important economic sector. Pali district in Rajasthan has got largest number of textile industries in the State i.e.989 units, mostly engaged in cotton and synthetic textile printing and dyeing. These industries liberate a variety of chemicals, dyes, acids and alkalis besides other toxic compounds like heavy metals, which are known for their hazardous properties. However, excessive and indiscriminate use of dyestuffs has become increasingly a subject of environmental concern. These dyes can enter the environment through the industrial effluents of dye manufacturing plants and from textile dyeing and printing operations, as wastewater effluents. Assessment of genotoxicity of dyes is therefore of utmost importance. Short-term genetic bioassays have proved to be an important tool in such studies because of their simplicity, sensitivity to genetic damage, speed, low cost of experimentation and small amount of sample required. A total of 7 dyes were tested for their mutagenicity, by Ames assay, using strain TA 100 of Salmonella typhimurium. Only 1 dye, Violet showed absence of mutagenic activity. The remaining 6 dyes were all positively mutagenic.

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Acid Leather Orange BZR 2429‐80‐3

2004

Sax's Dangerous Properties of Industrial Materials

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Mutagenicity of anthraquinone and azo dyes in Ames' Salmonella typhimurium test

Cited by 52 publications

References 12 publications

Structure Antimutagenicity Relationship of Anthraquinones

Structure Antimutagenicity Relationship of Anthraquinones

Assessing Mutagenicity of Textile Dyes From Pali (Rajasthan) Using Ames Bioassay

Acid Leather Orange BZR 2429‐80‐3

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