Mutagenicity of dieldrin in the Salmonella–microsome test

Abstract

Dieldrin was assayed in vitro for its mutagenic activity in several strains of S. typhimurium with and without Aroclor 1254 treated mouse liver homogenate (S-9M). The mutagenicity of the insecticide was expressed maximally in all strains in the presence of liver S-9M and less so in three strains without liver microsomes.

Mechanisms of environmental chemical-induced apoptosis in dopaminergic cells: critical roles of protein kinase C-delta and relevance to Parkinson's disease

“…On the other hand, another report using TA98, TA100, and TA1535 showed positive Ames results following dieldrin (1 j^g/ml) exposure (Majumdar et al, 1977).…”