2020
DOI: 10.3390/coatings10040403
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Mutated Human P-Selectin Glycoprotein Ligand-1 and Viral Protein-1 of Enterovirus 71 Interactions on Au Nanoplasmonic Substrate for Specific Recognition by Surface-Enhanced Raman Spectroscopy

Abstract: Protein tyrosine sulfation is a common post-translational modification that stimulates intercellular or extracellular protein-protein interactions and is responsible for various important biological processes, including coagulation, inflammation, and virus infections. Recently, human P-selectin glycoprotein ligand-1 (PSGL-1) has been shown to serve as a functional receptor for enterovirus 71 (EV71). It has been proposed that the capsid viral protein VP1 of EV71 is directly involved in this specific interaction… Show more

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“…As an example, Driskell et al used monoclonal antibodies as functional agents for the selective extraction of the feline calicivirus from cell culture media in a chip-scale, sandwich immunoassay, incorporating SERS readout [100] . Effective functionalisation with, for example, specific antibodies [101] , [102] , [103] and glycoproteins [104] has been demonstrated, while the use of oligonucleotides as recognition elements for SERS sensors has recently been reviewed [105] . An alternative approach of size selective capture by gold nanoparticle coated carbon nanotube arrays and detection using SERS has also been demonstrated [106] .…”
Section: Vibrational Spectroscopic Analysis Of Viruses and Viral Infe...mentioning
confidence: 99%
“…As an example, Driskell et al used monoclonal antibodies as functional agents for the selective extraction of the feline calicivirus from cell culture media in a chip-scale, sandwich immunoassay, incorporating SERS readout [100] . Effective functionalisation with, for example, specific antibodies [101] , [102] , [103] and glycoproteins [104] has been demonstrated, while the use of oligonucleotides as recognition elements for SERS sensors has recently been reviewed [105] . An alternative approach of size selective capture by gold nanoparticle coated carbon nanotube arrays and detection using SERS has also been demonstrated [106] .…”
Section: Vibrational Spectroscopic Analysis Of Viruses and Viral Infe...mentioning
confidence: 99%