“…Recently, our group described the accumulation of oxidation products in fibroblasts from subjects affected by MFS [2]. Although an excess of reactive oxygen species (ROS) has been invoked as a pathogenetic mechanism in aortic aneurysm and in other manifestations occurring in MFS [3][4][5] no study, till now, has specifically investigated the occurrence of oxidative stress in this pathological condition. Thus, we planned to measure protein carbonyl content (protein CO), accounting for ROS attack on proteins, and total antioxidant capacity (TAC), an index of total ROS scavengers, in the plasma of patients affected by MFS.…”