2024
DOI: 10.1002/adfm.202409883
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Muticomponent Melt‐Electrowritten Vascular Graft to Mimic and Guide Regeneration of Small Diameter Blood Vessels

Angelica S. Federici,
Orquidea Garcia,
Daniel J. Kelly
et al.

Abstract: Cardiovascular disease is a leading cause of morbidity. Current treatments include vessel substitution using autologous/synthetic vascular grafts, but these commonly fail in small diameter applications, largely due to compliance mismatch and clot formation. In this study, a multicomponent vascular graft, that takes inspiration from native vessel architecture, is developed to overcome these limitations. Melt electrowriting (MEW) is used to produce tubular scaffolds with vascular‐mimetic fiber architecture and m… Show more

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