With the impetus of flexible electronics and micro‐nano fabrication technology, the human demand for flexible intelligent wearable devices is on an upsurge. In recent years, new functional fibers have undergone rapid development and emerged as an indispensable carrier of flexible wearable e‐textiles. However, to achieve their functional applications and durability, new functional fibers must possess good electrical and mechanical properties. As an emerging two‐dimensional material, MXenes have attracted immense attention for their high electrical conductivity, mechanical strength, specific surface area, adjustable surface properties, and exceptional processability. As such, MXenes have become an ideal candidate for the primary functional component of functional fibers. This paper presents a comprehensive review of research progress on MXene‐based fibers in the construction of flexible wearable electronic textiles. Firstly, we briefly outline the preparation methods of MXenes materials. Next, we summarize the processing types of MXene‐based fibers and highlight their performance parameters. Lastly, we summarize the primary application scenarios of MXene‐based fibers and anticipate the future development of flexible wearable e‐textiles.