Myalgia

Abstract

Myalgia, a common symptom resulting from a variety of disease processes, often escapes a specific etiologic diagnosis. Despite the poorly understood pathogenetic mechanisms underlying myalgia, logical classification and clinical evaluation can lead to successful treatment in many cases.

COVID-19 in the intensive care unit: Unmasking the critical factors impacting patient survival

“…SARS-CoV-2 causes systemic inflammation and is believed to cause a rise in acute-phase reactants. 32 In the present study, inflammatory markers such as ESR and CRP were not significantly different between both groups; however, D-dimer was significantly higher among patients who died. Previous studies have shown mixed results on the prognostic value of acute-phase reactants in patients with COVID-19 in the ICU.…”

“…It is biologically plausible that myalgia and anorexia represent the host immune system adequately mounting a reaction to SARS-CoV-2 and may be associated with overall survival. 31,32…”

Case 22-1998

“…Cramps are sudden, involuntary, painful, self-limited, nonspecific muscular contractions originating at multiple sites, including the anterior horn cell, peripheral nerve, and muscle. 15 Cramps that occur at rest are common in otherwise normal persons; their meaning in isolation is difficult to gauge. "Growing pains" in children are similarly benign and are usually confined to the legs.…”